So was I. Essentially, if you can go 50 ly in 1 million years under constant acceleration, then it would take ~450,000 yrs to go 10 ly starting from "rest".
Waiting until you get warning of an imminent supernova is likely not an option. But that doesn't mean we couldn't try and keep our distance from supernova candidates. We know that only stars above a certain mass supernova. So maybe the strategy would be "Why wait for trouble? Let's just keep our distance from any stars that could even possibly supernova."
Pluto shouldn't be left behind. If we go by the 50 ly in 1,000,000 year at constant acceleration scenario, then the acceleration needed is 4.27e-10m/s2, While the centripetal acceleration for Pluto is 3.8e-6 m/s2, several magnitudes larger.