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Showing content with the highest reputation on 02/13/23 in all areas
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Haha. However I don't think this general quite meant that. I think he was trying to stop being dragged into speculation by the line of questioning of a reporter and tried to close it down by saying he would not rule anything out until he had the intelligence reports. Unfortunately that included not ruling out little green men. So now everyone has jumped - either stupidly or disingenuously - on that, to claim "Aha, he thinks it could be little green men!"2 points
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The details are actually quite complicated, but I can start simple (and my apologies if it is too trivial) and maybe start with comments on some of the trickier parts. As you mentioned, the terms LDL and HDL do not refer to the cholesterol itself. Rather, cholesterol is transported packaged by lipoproteins, the mentioned high-density lipoproteins (HDL) and low-density lipoproteins (LDL). In addition there are also very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL). The measurements therefore refer to the fraction of cholesterol associated with particles of specific density that circulate in the bloodstream. To complicate matters on this level a bit, there are slightly different assays that measure the fraction of LDL in different ways (often indirectly, e.g. using the Friedewald equation, whereas direct methods often also measured IDL and VLDL). There is some data suggesting that using ApoB (which only not associated with HDL) could be a better biomarker for cardiovascular health, but that is under discussion, too. But one way I think about VLDL- IDL-LDL is that they are different maturation steps where the very large VLDL are reduced in size and then can enter the intima. Now, originally it was believed that LDL is a transport vehicle to move cholesterol to peripheral tissue and organs and HDL moves surplus cholesterol back to the liver. In part, the idea is then that very high LDL-cholesterol leads to deposits that can cause arteriosclerosis, for example. However, when trying to look at associated mechanisms, things get complicated pretty fast. For example, it was found that the vast majority of cells actually have an active lipid metabolism and most cholesterol are produced where they are used and are not necessarily delivered via LDL. Then, there is the issue that a lot of LDL cholesterol is derived from HDL and a lot of them is taken up by LDL-receptors in the liver. I.e. of the LDL is actually directed to, not away from the liver, making it questionable whether delivery to the periphery is really the main function of LDL. Likewise, HDL has been known to be critical for cholesterol efflux capacity (removing cholesterol from macrophages and transport to liver), but now studies suggest that LDL amplifies these efforts by HDL pathways. So taken together, the classic dichotomy of LDL vs HDL (cholesterol) has become rather questionable but we do not have a fully articulated model yet that can be used for better health prediction. Edit: I should add that my expertise is mostly limited to biomarker analysis, and not the clinical aspects, so it is therefore biased a bit more on the molecular/analytical side and may not reflect clinical standards. Therefore none of it should be considered medical advice of any sorts.1 point
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Also like some of their raunchier songs, which I will warn may be NSFW.1 point
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I have a saying, "You can't think out of the box until you understand what is in the box".1 point
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Does not seem so: Anatoly Chernyaev. The principle of the golden section (delachieve.com) Yes, independent of science.1 point
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Inelastic refers to KE, not momentum. A wall effectively has infinite mass, being anchored to the earth. Up until it breaks apart.1 point
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No one is laughing at you. You have some good thoughts. One definition of a dimension is "the number of independent pieces of information (co ordinates) you need to specify the position of a point. So you need for instance one distance from 1 point in 1 dimension, two distances from two points in two dimensions, 3 distances from three points in 3 dimensions and 4 distances from 4 points in 4 dimensions. But eyes are not points, as Genady says they have visual overlap - they are two dimensional patches. This is how the brain can get the extra information requires to measure in 3 dimensions. Again but as swansont says, 4 dimensions introduces extra complications so more detail is necessary.1 point
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No. Two eyes allow to estimate a distance to an object in 3 dimensions, 2 dimensions, 4 dimensions, etc. You have a triangle with the known length of one side and two angles. From these, the brain computes the distance.1 point
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The balloon collected intelligence about how the U.S. responds. They watched the ballon cross into Alaska and how we responded. They watched how the government and military responded the entire next week. They watched the news coverage and national freak out on social media. The conspiracy theories that were most cited. The anger and disappointment at Biden. They watched family members sniping at each other. They watched what other things and places we stopped watching while watching this. Now the next time when they want to deploy a virus against our banking system or energy grid, or just want more leverage in a negotiation over carbon credits and trade… they’ll just float a balloon across the continental US so we look up and watch it like wide-eyed children. “Oooohhh… shiny!”1 point
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Just a thought. If I really wanted to make black people look stupid, I'd post that video clip without mentioning that it's fake. I'd let people think that it illustrates a real incident where a group of people did something monumentally stupid. (Rather than it being an advert for a film.) 83,048,009 views 6 Jul 2011 In theaters now! Purchase tickets online @ http://www.fandango.com/riseoftheplan... ---------------- http://www.facebook.com/apeswillrise - For the latest 'Rise of the Planet of the Apes' news & updates ------ http://itun.es/igb4Ky - --- Soldiers give monkey a loaded gun From https://www.youtube.com/watch?v=GhxqIITtTtU In broad terms, do you think that video clip is more likely to be quoted out of context by racists or non racists? Which group do you want to be seen as part of? In broad terms, does the video that purportedly shows a group of black guys being really really stupid (without making it clear that they are paid actors) play in favour of, or against, racism? So, OK I apologise. I was too subtle in pointing out that (without context) the video is "too wrong to be funny". That video is deeply offensive. I really think that the best thing to do is either clarify that the video is deliberately fake or take it down. (Not everyone will realise that a chimp wouldn't be able to handle the recoil of a real gun; nor would they calmly ignore the noise it made) I also apologise for not realising the full extent to which people would be offended by the way I did that. OK I really am sorry about that. I'm also sorry for any offence I caused.-1 points
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I don't believe you or anyone in this forum is really interested in science, just repeating what anyone can read in wikipedia. I certainly understand SR and I certainly don't need to learn about it from people on a forum, I read the actual articles. But I suppose you can explain Einstein's theory better than him. Anyway, I'm obviously wasting my time here, so go back to rehashing wikipedia pages to people who haven't heard it exists, because I won't be posting here anymore, ever, none of you are worth the effort.-1 points
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IMO, and I've studied both heat pumps and heat engines for a very long time, your comment only demonstrates a lack of understanding regarding the details of how either machine or appliance actually operates. These "Ideal" scenarios of a heat pump actually being a heat engine running backwards are about as silly as saying: if you turn the crankshaft on your lawnmower backwards it will produce gasoline. A heat pump running backwards is an air conditioner. All either one does is move heat one way or the other. A heat engine consumes heat. Creating cold by moving heat out of an insulated space is not the same as creating cold by converting that same heat into mechanical work output . In a heat engine the heat does not disappear at the evaporator and reappear at the condenser. It just disappears. Period. Consumed as "fuel" to produce a mechanical motion. The cold produced by a heat engine is not the result of simply moving the heat through the engine from one side to the other, taking it in at the heat source and transporting it over to the sink. The cold produced by a heat engine is the result of destroying the heat, so that it no longer exists. You can't push your car backwards to fill up your gas tank.-1 points
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I have a saying,"To not think out of the box is to always be in the box". There has been a longstanding conundrum with regard to the notion of nothingness represented by zero. As we have seen, zero is both real and imaginary. If what I am saying is correct, there is an inverse universe equal and opposite to ours. This helps to explain entanglement. We should also consider the fact that there is no such thing as "nothingness". This has been pointed to by theoretical mathematicians. If there is an inverse relationship, then all that can exist closest to nothingness is both real and imaginary. By the way, my apologies for incorrect grammar at times. I often use dictation software. It seems to me that the first resolution should concern the "divisibility by zero conundrum". Instead of having zero represent nothing, a better representation should be an infinitely small, but not zero, superposition of real and imaginary -- (Schrodinger's Cat).-1 points
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Infinity is a difficult topic, granted. Effectively, it is the superposition we are trying to find. The point of superposition probability in quantum physics (equal probability of the cat being both alive and dead at the same time). Exchemist, is it you alone who can think about these issues? Must you squander out of the box thinking in a speculative forum? A great service to science you are.-2 points