Hi all!
I'm new here and coming from university with a great interest in immunology with interesting question to pose.
If we were to create an antibody that bound to, and effectively blocked, the function of a (extra cellular) protein that was synthesized (naturally) by our own bodies. Would the immune system be capable generating memory B cells and replicate these antibodies on its own to prevent the need for further treatment? If this is something that may not occur, would there be a mechanism by which an injection of these antibodies and some other substrate result in the body adapting to the introduction of these antibodies and produce its own? Effectively becoming an auto immune disease if I am correct, but if these were to be monoclonal antibodies surely the specificity would be retained?
Sheesh that was long winded! Thank you all for reading and answering!
Feel free to make comments on the question and whether or not I could have posed it differently, it's late here so I'm sure I could have.
Jordan