This is a very simple way of putting a stop to just about any conspiracy whack job:
Ask them what proof they will accept as truth they are completely, and utterly wrong. If they are intellectually challenged, which I assume they are, then word it as: If you gave them a piece of paper right now, that convinced them they were wrong and science was right, what would that paper have to have on it?
This will generally silence all, but the most delusional. If they can't provide you with anything, then it is proof of a mental illness (I believe this more or less matches the definition of "insane") Anything they do say, can most likely be found fairly quickly.