I am a trainee in a company which is producing 2-chloro-4-amino sulfonamide.
They start with meta chloro aniline & did chlorosulfonation with CSA (chlorosulfonic acid) followed by SOCl2 (Sulfonyl chloride) & then amination using ammonia.
When I referred Vogel, I found that
R-H + ClSO3H = R-HSO3 + HCl
R-H + 2 ClSO3H = R-SO2Cl + HCl + H2SO4
Where R - is aromatic benzene ring.
Since Company is already using 8 times of theoretical value why they are using sulfonyl chloride.
The product is formed like this
R1-SO2Cl + NH3 = R1-SO2NH2 +HCl
Where R1 - is meta chloro aniline radical kind of structure.
Can anyone help me.
Can I use any other starting material for this product
