Cristian Ramos

on the other hand, the mitochondrial apoptotic life is induced as a response to cellular stress and results in the activation of pro-apoptotic BH3 proteins only the BAX and BAK are two encoded nuclear proteins present in the higher eukaryotes that are capable of forming the outer motocondrial membrane to measure cell death by apoptosis, is there in this mitochondrial outer layer some factor or regulation that protects it and does not allow the entrance of these two nuclear proteins and therefore avoids the process of apoptosis?

but it is known that in the cell cycle, there are some control points, to avoid and correct possible defects of this cycle, then what explanation is given of errors that happen and are not corrected.

but if there is no activation of these protein complexes that activate apoptosis or cell death, it is carried out: saturation of diseased cells, mutations .. etc or as apoptosis is regulated

WHICH PAPER PERFORMS THE DOMAIN OF PROTEINAS BH3 ABOUT THE BAX AND BAK COMPLEX FOR THE ACTIVATION OF THE APOPTOSIS PROCESS. AND IF THERE IS NO CATIVATION OF THESE PROTEINS THAT WILL HAPPEN, DEVELOPMENT WILL BE UNCONTROLLED. ?