Hello dear friends!I have a question about a reaction route in my thesis. I am synthesized thiosemicarbazide then in alkaline/acidic medium is synthesized from thiosemicarbazide to triazoles/thiadiazoles.However alkyl isotiyosyanate as methyl/ethyl/cyclohexyl can be thiosemicarbazide, 2-pieridino ethyl and 2-(4-morpholino) ethyl isothiosyanate isn't thiosemicarbazide and is directly transforming triazole. But I don't want to direct this cyclization. Because thiazdiazoles obtain from that thiosemicarbazides.I want to get morpholino and piperidino ethyl thiadiazole. May are you doing advice this difficult problem. thanks everyone !
