Hi Folks! I'm a newbie in this forum, I hope not to violate any rule with this post, in the case I apologize in advance
I've got a list of doubts about Immuno exam, I am a Med student
1. what is the role of lectins and agglutinines in innate immunity?
2. entrance of immature T in thymus happens via blood?
3. once T mature in the thymus, thymus then athrophyzes. Where does maturation for the next T happen? I haven't got this clear... is it like for the oocytes? they just mature all once and that's it?
4. innate immunity: what are preformed effectors? [Janeway] are they AMP?
5. CD40:CD40L is it a stimulating interaction from T towards APC? has it other functions?
6. Can DC be found in blood?
7. Th acivate B. OK. Do B in turn activate/stimulate T? as "late" APC?
8. only IgM and IgG activate complement? what about IgA and IgE?
9. how many MHC2 on a DC?
10. definition of antagonist of a cytokine
11. pH of phagosome = ? I read that pH [i.e. neutrophils] goes above 8, activating AMP, then gets back to 7, then below 7 because of acid hydrolases...
thanks from heart to everyone will explain me some of the above doubts!
