I'm merely a student of evolutionary biology but this article reads like an alarmist piece. And because it's not peer reviewed it carries no weight with me. I suspect were it presented for scrutiny we would find that most mutations are harmless and any harmful ones eliminated quickly. If the opposite were true many species would be seriously hindered since only a limited amount of offspring would survive to reach sexual maturity. Perhaps humans have found a way to increase harmful variations within our own genus but it's only because those born with defects in fitness reach sexual maturity instead of being eliminated. If natural selection is not permitted to function the fitness of any species will suffer.