Hello
As my profile name suggests, I'm very interested in lavender, and especially the medicinal properties. I'm making a presentation about the medicinal properties of the compounds in lavender. (Primarily terpenes, with linalool & linalyl acetate being the most prominent.) And I've gotten interested in one property in particular: anti-psychotic.
Now my question is: is there any scientific evidence for the possible anti-psychotic properties of lavender?
I found several sources claiming that linalool has anti-psychotic properties.
https://abstraxtech.com/blogs/learn/what-is-linalool-uses-and-benefits ("Linalool is considered to be an excellent: Anxiolytic, Sedative, Antiepileptic, Antidepressant, Anti-inflammatory, Analgesic, Antipsychotic")
https://www.oblend.com/terpenes ("Linalool has been found to be helpful in the treatment of both psychosis and anxiety.")
https://labeffects.com/terpene-glossary-linalool/ ("Antipsychotic: tranquilizing effects reduce symptoms of psychosis")
https://www.harmonydispensary.org/linalool ("Linalool lessens the anxious emotions provoked by pure THC, and may be helpful in the treatment of psychosis and anxiety.")
https://hempsley.com/blogs/science/an-introduction-to-terpenes-in-herbs-and-cannabis ("Therapeutic properties: anti-inflammatory, anti-epileptic, antipsychotic"
Lots of cannabis-based websites claiming said anti-psychotic property (linalool also occurs in cannabis, hence the many cannabis websites); but I can't find scientific studies to verify the claims of said sources.
I did find this study showing an interaction with D3-receptors https://pubmed.ncbi.nlm.nih.gov/19560529/ , while general pharmaceutical anti-psychotics tend to antagonize D2-receptors. Both D2- and D3-receptors belong to the 'D2-family' of receptors. https://en.wikipedia.org/wiki/Dopamine
Maybe there is a link?
I also found this about the 5-HT1A-receptor: https://www.psychreg.org/lavender-oil-reduce-anxiety/
"Brain scans using positron emission tomography show that lavender oil works via serotonin-1A receptors in the brain, reducing their binding potential so that levels of free serotonin and related neurotransmitters rise, resulting in reduced anxiety."
Thank you in advance.
