I started reading about how genetics works at the cell level on the web, but I need someone to answer some questions I have:
1.Genes produce receptor proteins, which then bind to the neurotransmitter or other chemicals. What happens then? How does this then cause the neuron to either fire or not fire? A link to a Wikipedia article would be fine.
2.Genes have often have thousands of base pairs, so how come in genetics research they usually only have 2 variations of a gene? Could you point to some descriptions of how different variations of a gene produce different amounts of receptors at a molecular level?
3.Are genes each responsible for only one thing? If that is true then different alleles for a neuroreceptor gene would basically only control one thing, the quantity of neuroreceptors produced, right? So if, for example, a certain activity had been shown to up-regulate this gene, would that essentially have the same effect as switching this gene to an allele which produced a higher number of those receptors, or somewhere inbetween?
4.For example, lets say a gene exists for which there are two alleles A and B, A produces less receptors for neurotransmitter X, and B produces more, and is associated with a 5 point increase in IQ compared to A. Lets say a person has A. Lets also say that sleep deprivation has been shown to up-regulate production of the neurotransmitter X receptor proteins. Would this basically have the same effect as switching the allele to B?
5.If this is the case then all you need to do to change help certain diseases, and give yourself genetic advantages is to find a gene which has been shown to be associated with that area, and then find an activity or nutritional supplement which can affect the regulation.
6.How many practical things are there which have been shown to change regulation significantly?
7.I know that the BDNF gene can be up regulated very significantly by sleep deprivation, exercise, and antidepressant therapies.
8.How often does gene regulation change? Does it change constantly, and can you attribute most changes in your thinking patterns to a gene regulation change?