Guys I have a problem in understanding a discussion with my fellow class mates. He said that "Fact is, supplementing with AKG won't do squat unless you are using something like a membrane permeable ester theoretically. The metabolic intermediates exported from the beta-cell mitochondria into the cytosol have the insulin-releasing signal."
I know he is wrong because I readed some studies which I know go against what he said. But is he really wrong ? I asked my teacher he told me to follow up these two links for help but I still don't get it.
http://www.ncbi.nlm.nih.gov/pubmed/19502541
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCH-4J026P4-2&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1160166844&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=15ab9dd0034e6fad1d22bcd3819e829d
How do I tell him hes wrong ?
I am sorry if my english is not sound, as it is not my first language
And once again, please I would really appreciate some help