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genenerd

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  1. genenerd
    the Constant Spring allele of the alpha-globin A2 gene produces a protein that is 172 aa's long rather than the normal 141. The first 4 amino acids match normal alpha-globin, but aa#142 in Hb-Constant Spring is glutamic acid. What is a possible hypothesis to explain the mutation that created Hb-Constant Spring? What is going on in the DNA in transcription and translation?
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