In evolutionary terms 1000 years is not very much at all.
It is however time enough for small changes due to natural selection alone.
We are unlikely to see speciation in humans even by 12,003 (considering how long homo sapiens sapiens has been around), but you never know.
Adaptive changes are likely to involve a massively reduced jaw size, almost hairless body, thinner longer limbs, and larger eyes.
We will probably have a simpler digestive system that is no longer capable of breaking down complex organic structures.