scicop

I'll be the first to agree, security blows across the nation, however it has gotten better since 9/11. I also include intelligence (gathring of information pertaining security) within security. DHS has its pitfalls, but I think overall it has been a good thing. Local governments need to step up to the plate in order cover DHS blind spots and the City of New York has done a fine job filling in the blanks, i.e. NYPD has its own police officers stationed abroad for intel gathering, in addition they also have a Joint Terrorism Task Force that fosters communications between the PD, and the Intel Comm. While cities more prone to terrorist attacks should obvious y get more funding, less favorable "terror-target" cities can helps themselves at least with security. It only takes one PO, or gov't delegate to liase with the IC! My apologies for the "fly over" comment, I should be the last to make that comment. Last year I took counter terrorism training given by the JTTF, their introduction, included a section called the "faces of terrorism". Their first picture was a white middle-aged woman, from a pro-life terror campaign. Their next was a Japaness guy..(mr. sarin explosion dude), their final picture was Osama (after like 10 others of people with diverse ethnicities and countires of origin). .....so sorry for the comment..pangloss is right with his assertion.

ha ha..you go DAK!

Yeah..states like Nebraska and Wyoming need to feel important. Terrorist, just like normal US citizens, will "fly over" them states. Wasted money.

on more thing....in order to succeed in science...you HAVE to be CREATIVE!! When I was in grad school, my Ph.D. mentor said to me the following: "To be a scientist, you have to be more than a technician, a technician is not a scientist, rather a scientist is also an ARTIST, A philosopher, a writer, AS WELL AS a great technician"

Still insufficient. Its not the way its done. As ecoli said you would have to get a purified compound/"activity", and perhaps elucidate its structure. I think you're barking up the wrong tree with the garlic idea. You're not the first to investigate the topic, as many have gone down your path. Big pharma is really pushing their natural product development for new compounds, so you're pretty much a little fish in a big big big pond. The intel comp is looking for novel thinking/novel approach not just novel findings. You need to think of a problem a really nice way to eludicate a solution. I don't know how much time you have but read scientific magazines such as science and nature. Although the questions the papers address can be answered by a number of conventional techniques, they are highly differentiated by the approach the scientist use to address the question. For example, controlling gene expression in cells (in vitro) has had its caveats due to efficiency/proper control. Its been observed that gold particles of less than 15nm in diameter are readily enter cells, although the mechanism has not been elucidated. Last week in science magazine, scientist, figured out that they could attach anti-sence DNA to the gold particles and knock-down gene expression (in vitro) at almost 100 percent efficiency (number of cells with observed phenotype). So, its already been known that antisence DNA can attenuate gene expression, and gold particles at that diameter enter cells, and delivery has been a problem for scientist, so these dudes put two and two together and bam!! an elegant set of experiments to help put forth a probable way to circumvent the problem! So basically building on knowledge we already have, but doing in a smart manner! Try taking that approach. Identify a problem, take what is known, generate a hyp, and test it! Welcome to the world of science! This is what being a scientist is all about..elegant ways to investigate a question/problem!

I'll go with the wound licking!! But on a serious not I highly doubt there is a totally right answer to the question, at least from the Cambridge University point of view. Getting the answer wrong would not determine your acceptance, rather how you answer the question is more important! They are looking for how you think and the logic you use behind the question. This is tactic used by alot of top companies today, during the interview process (i.e. Mackinzie, Boston Consulting Group, Citigroup, Pfizier, BMS, AstraZeneca, even NYPD). They ask case study questions, field related such as "estimate the market size for a new tire specific for harley-davidson in the north-east US and determine probably pricing" , as well as weirdo questions such as "how many golf balls can you fit in a submarine"! The interviewer has the answers to the cases, but that's not important, they're looking for what questions you ask, how you put the story together, and how you arrive at your conclusion! Same thing for graduate school interviews!! Often they'll ask a science related question, and they'll ask you what experimental approach(s) you would use to investigate say for example "G-protein independant activiation of p42/p44 ERK by H1-histamine receptors" So I think getting the answer "wrong" wouldn't block acceptance. Rather how you address the question. With that, I gladly decline my acceptance the Cambridge U, I'd rather Oxford, or the Southwestern University of Philippeno, Mexican, and Tanzanian Microbial Neurobiology.

Here's the "honest" truth....... this is one I hate. I guess the truth would be dishonest? Oh yeah..and I KNOW the truth. I'm just not telling.

I'll take a stab, so thinking about WWI, I imagine the soldiers were down in the trenches in the mud, were gangrenous bacteria survived. Gangrene was a often a cause of death in the trenches, perhaps more than bullets I don't think that's been substantiated. There was a lack of antibiotics on the field. Thus I gather they may have spread the jam to promote the growth of fughi/mold that produced antibiotics (pennicillins), which would combat the gangrenous infection. And thats my guess..promote fungus/mold formation as a means for antibiotic treatment!

I wonder how come big pharma has not invested in understanding the proximal/distal axis development of fine organ. Its got a DV axis as well, so I imagine there has to be an Apical Ectodermal Ridge (AER) at its tip during dev. If we can tap into perhaps AER signaling (notch/delta) at the penis (in utero) we can get some might big ones popping out no? I'm sure parents would pay for thier sons to have a bigger one! come on big pharma....hop to it!!

Chatting with a minor is not illegal, but once the conversation becomes sexually explicit and/or exchange of sexually explicit data with an minor, then it is illegal and subject to prosecution. It does not matter if the "minor" is an adult pretending to be a minor. It is not entrapment. The fact that the perp thinks he/she is talking to a minor is irrelevant. When the perp engages in sexually explicit conversation with a minor, it is sufficient for prosecution. My department not only has their own child abuse task force unit, but also collaborates with other agencies in sting operations, including the various county SPCC's (society for the prevention of cruelty to children) and federal agencies such as US Postal Inspectors. So, its a good think that those guys are out there! Alot of unsung heros out there!

With respect to your garlic idea, the best would be to actually isolate the "activity", that is implicate a compound. This would be a big project and you would have to find a prof. with expertise in column chromatagraphy, HPLC, and NMR, access to such equipment, and willingness to train you. You would develop an assay to screen the "activity" various extracts, starting with solubility (i.e. methonol soluble compounds vs. h2o soluble). Once you found your fraction with "activity", you would then initiate the identification process. These techniques are often utilized within the "pharmacognosy", "fitochemistry"or "natural pharmacology" fields. Most of these studies are conducted in either in big pharma and in academic settings within latin american/european countries, however there are a few academic labs in the US that do such undertaking, ususally housed within the dept. of chemistry in those universities. The use of just "whole" garlic in your experiment wouldn't be sufficient for the intel comp.

Put a plastic bag over your head and make sure its air tight. Breathe. Keep breathing until you're gasping for air. Do not remove the bag under any circumstances. Right before your death you should see some cool hallucinations. Sigh..this is one awesome way to weed out the dumb..don't know why we as a society don't promote such activity to dumb teenages. I expect to read about at least 10 deaths tomorrow regarding this techniques...common kiddies..don't let "scicop" down!! DO IT!!

Although the initiating causes of schizophernia is unknown there has been some progress in understading its orgin. Gene expression studies using a combination of DNA microarrays and brains of deceased schizo patients (screened for schizo, eliminated for other pyschological conditions) have revealed profiles consistant with altered mylenation, the glial process of surrounding neurons for physiological and electrical support. Work by Ken Davis MD (mount sinai school of med) and New York Psychiatric Institute have published said data.

Nah..maximum 15 to 20 million if that for your entire company, shared with all of your investors (university, venture capitalist, angel investors) and you. (your cut..probably a 2 mil) Once you have sufficient pre-clinical proof of concept, a large pharma will probably buy you out..and most likely you'll sell, because they have the resources to do the clinical (phase I, II, III) parts of drug development which is VERY expensive. Not to mention the branding, and pre-launch activities. Rare today do biotechs make it to clinical fruition without being asorbed by a big pharma Most of your money would come later on, as other biotechs bring you on to their advisory board since you would have had a demonstrated track record. However, if you are able to get sufficent investments/loans and you make it to IPO with major drug launch..then you're cashing in big time. Of course none of this is easy. Most scientist are not businessman and VCs are fully aware of this. Most often the inventor is not in charge of the company they found!! VCs step in eventually and take over management.

Don't be an idiot and drink your self silly. That's the simple answer. No matter if the damage is short-term or long-term, its still a dumb idea. Very dumb. I'd say retarded, indicative of a person with sub-human IQ.

Um..no you DO NOT NEED a MD to be a neurochemist! what ever that is. If neuroscience is your thing, then that's what you do!! pursue studies in the field of neuroscience. A BS or MS will get you in the door at many pharmaceutical companies, you just need to apply to their neurosciences division. In addition, you can get into an academic laboratory and conduct research as a technician. If your interest go more deep and you wish to examine a more specific question in neuroscience you can pursue a Ph.D. degree. You can choose a mentor whose research interests agree with yours. The Ph.D. will open more doors for you. Most basic neuroscientist in industry and academia are PhDs. The MD will allow you to pursue "neurochemistry" much later on in your career, as that is a clinically based degree. Usually strait MDs pursue research after their residency if they want since there are special NIH grants that support the development of physicians into scientist.

"I Have $$$"!!

this tread is funny!! its so TRUE!!! Especially here in NYC....you can't imagine how many sniffs I hear on a daily basis!! Usually it happens right when your equal or slightly past the person! Females do it just as often as males. Go figure.

That's why i'm doing a G-job! Ye ole NYPD motto...20 and out!

I think there are missing components to the question. If i'm correct those sequences are stop codons. Thus one way to assess mutagenecity would be to place those codons in frame with a reporter gene (i.e. gfp, lucierase or antibiotic resistance). You would have to design primers that flank both 5' and 3' sides of your stop codons and use sequencing analysis in your transformed mutants (if any) to assess what base changes were made. that's my take given the information you gave, but how that would related to DNA Pol "V" activity, i'm not sure, that's a whole different question. UV tends to make pyrimadine dimers (between Ts), and inorder to assess DNA Polymerase activity past such lesions you would have to conduct kinetic assays, which have been done my many others in the past (see work by Kornberg, Grollman, Teebor, Sietz). Good luck.

There are no black color centers. It is the lack of signal. Also, the reception of light, at least at the light receptor (cell) level is inhibitory! With respect to perception, well that's the brain! Color assignment is purely brain manifested response/assigntment to light stimulation at defined frequencies (i.e. 488nm for Green, 570nm for yellow, 600nm for red etc. There are wavelength specific receptors (rhodopsins, member of the Family A superfamily of G-protein coupled-receptors) which depend on light energy for conformational change. Since black is not a color (in a physical sense..no wavelengths etc) then there is no way of activating any color selective rhodopsins. Hope I'm clear here.

Check with the New York Academy of Sciences, they may know of something. Also, check NYC Dept. of Education, Central Park Conservancy, The various schools of medicines and graduate biomedical programs, as they may have opportunities for you. You can even try volunteering in a research laboratory! NYC has quite a few universities engaged in top biomedical research, i.e. nyu, columbia, weill-cornell, memorial sloan kettering, mount sinai, rockefeller. You can call up other city agencies and see they have anything, NYPD runs a biomedical/chemical lab in queens. OCME has their labs right next to NYU med. NYC Dept. of Public Health runs research labs as well and may have course work. There is also the NYC Office of Science and Technology you can call. So, do some phone calling, you never know what you can get!!