hypervalent_iodine

What have you come up with? What have you come up with?

Think about what sort of reagent KOH is and what it might do to the starting compound.

ferdinand1981 and fox1981 have both been banned as sock puppets of jugheadjones13

! Moderator Note I am closing this an giving you the opportunity to rewrite your OP in a way that is coherent. What you have written here is extremely difficult to read, and for the life of me I cannot work out what you want to discuss. Please be more concise, and make better use of paragraphs.

What do you think compound E is? Could you draw it?

DCM is not something I would use outside of a hood unless I was putting it on a rot evap. I think you are probably okay, but if you are uncomfortable with people using it outside of a fume hood, I would speak to someone about it. If you are concerned about symptoms, you should see a doctor. Also, regarding your question about the silica plate - it does not give an acidic smell, but I would avoid the dust. Small bits from cutting plates aren't anything to worry about, but larger amounts of free flowing particles (for say, columns) you should be mindful of and only work with inside a hood.

It has a very distinctive smell, but I wouldn’t call it acidic. I have inhaled DCM before and from memory it can sting a bit, but it isn’t lingering. I believe the main problem with it is more the long term effects from constant exposure, anyway (as well as environmental concerns). Was / is your hood working - i.e was it sucking in air? You can check by getting a bit of paper towel and seeing if it is pulled into the hood when held just under the sash. If it is, and if everything was fully contained to the hood, you shouldn’t have inhaled much or any. The culprit may be something else in the lab. Did you let the plate dry fully before developing it? Side question, 50 mL for a single TLC?! Are you doing prep TLC with huge plates or something?

! Moderator Note I think it is probably best you don't post about this again until you have something that is at least approaching complete. Until you are able to come back with a testable model and a fair bit more math, this is closed.

HCl is soluble in ether, however it is also quite volatile. Vacuum would have removed it.

It is very, very unlikely that you have anything form the acid work up left.

Perhaps you could explain this a little more scientifically, as I am having trouble trying to figure out what you are talking about. Perhaps I am misunderstanding what you are talking about here, but ligands that bind to metal centres frequently are charged species. EDTA for example, is generally in charged form (Acetate groups posses a negative charge) when it chelates to metal centres.

! Moderator Note I'm sorry, this isn't a place for medical advice. Please consult a specialist.

! Moderator Note We don't allow members to make posts seeking medical advice. If you want to use this thread to discuss the general relationship between barometric pressure and pain (I think that's what you're asking, it's not exactly clear what you are referring to when you describe something as being worse), then that is fine, but you are not to use it to gather possible treatment options to help you overcome what you are experiencing.

! Moderator Note For the record, thread necromancy is not explicitly forbidden in the rules, but it is frowned upon, especially when the necromancer adds nothing new to the conversation. YaDinghus, it would be greatly appreciated if you slowed down on it a little. You are often responding to OP's who haven't been here in months or years, or are contributing points that have already been covered at some point in the thread. While I welcome your enthusiasm, I think that if you wish to discuss things brought up in old threads or posts, you can quote them in new threads and start new discussions around them.

The top one looks like a heating block for placing vessels into for incubation or evaporation. It would be placed into a heating mantle and is designed to be removable so you can change it out for one with different sized holes. We use similar ones for evaporating solvent from samples in vials. Unsure exactly of the bottom one, but at a guess I’d say it’s designed to be held over a Bunsen flame or similar.

How exactly is this a philosophy subject?

If you already knew that, why did you ask the question?

! Moderator Note To be honest, there aren't a lot of females who frequent this website. You may be better off going somewhere more targeted to the advice you are seeking. Regardless, we are not a forum that dispenses medical related advice and as such, I am forced to close this thread. Sensei, it is not your business why people want to have children. In the future, you should keep those opinions to yourself.

I don’t really see the benefit over normal BMI calculations. You still appear to suffer from the same major problems, namely that a “good” BMI is not one size fits all when you account for muscle weight etc.

Ren1000 has been banned for abusive behaviour.

! Moderator Note We’re done here.

! Moderator Note No one has time to read that. Could you Kindly provide small excerpts containing the bits you are confused about, with a link to the original text?

I meant temp and time used. What is the mass recovery like from the column? You mean in the combined organic layers prior to drying? If you get product out after drying, I’m not sure that means anything. Is there anything in your aqueous layer that could be product? You can switch to Na2SO4 if you’re concerned.

I honestly don’t think that removing MgSO4 is going to change much given how low your yields are. How soluble is everything in your reaction? Have you tried altering the conditions at all? How do you monitor the reaction?

Unless you are using a lot of MgSO4, I don't see it being the problem. The thiol may be a problem. Have you looked through the other parts of your reaction to see what else is present?