Overbearingminds

If k is a positive integer and if the numeral in the decimal system that represents the product 60k contains only the digits 0 and 2, what is the least possible value of 60k ? If this question was asked in a multiple choice exam, one would simply take an answer and find if it is a multiple of 60. What if there were no answers given? For instance what if the question asked to find the first 5 multiples of 60k, that which 60k contains only the digits 0 and 2? The possibilities are not endless, but wouldn't it be rather difficult to pinpoint them? Thanks in advance.

mTOR signaling tells Cyclin E we are about to replicate DNA but there are no Amino Acids. If mTOR signals are not present and you replicate DNA.....apoptosis will occur.. Why is this the case? and is TGF-B signaling needed and why?

"The most sensitive amplification methods use an enzyme as a marker molecule attached to the secondary antibody. The enzyrne alkaiine phosphatase, for example, in the presence of appropriate chemicals, produces inorganic phosphate that in turn leads to the local formation of a colored precipitate. This reveals the location of the secondary antibody and hence the location of the antibody-antigen complex." Does this imply that the enzyme alkaline phophatase reacts with the antiboy-antigen complex (the entire complex when assuming indirect immunocytochemistry) (the appropriate chemical) and in turn it leads to a colored precipitate?

interior of ER Golgi is topologically equivalent to exterior of the cell This exterior.......is it extracellular fluid? Interior of ER is Lumen?

Perfect! Just what I needed to know! Thanks Horza

To make a long story short E1 (a protein) reacts with Ubiquitin (another protein) and covalently bonds via a cysteine residue....what type of reaction mechanism are we looking at here? The reaction is ATP dependent if it helps. Thanks a lot in advance.