purplepeopleether

Im not sure if the R on the Nitrogen should be there in the product or not, but this the the scheme that was drawn by my organic chemistry professor. I figured that I would need a strong base (some of the research that I have been looking at used n-BuLi) but I'm just having a hard time figuring out what the electrophile would best look like, theoretically. I've searched on scifinder for similiar molecules to the product, but unfortunately have not had great success. As for the enzyme that I'm trying to inhibit, I wasn't told of a specific enzyme or group of enzymes by my organic chemistry professor. I'm just trying to figure out what would work best theoretically and then see if I can actually make it. This is a research project that I am doing as a chemistry major in my freshman year of undergrad, so any help would be greatly appreciated! Thanks in advance!

I'm doing research on the phosphonylation of disulfonimides for the synthesis of novel enzyme inhibitors. Has anyone ever done similar research?