Hoose

Well, I'm pretty sure FAS ligand downstream components a cleave procaspase 3 into caspase 3 which cleave ICAD into CAD, which enters the nucleus to chop up DNA, but I still don''t this NO blocks FAS pathway.

Il-2 is a T cell proliferation cytokine. deficiency in its production or lack of receptors for it on T cells will prevent T cells from proliferating when activated resulting in an inability to respond to infection sice T cells are important for cellular and (activation of) humoral immunity.

Viruses are small enough to pass across the placenta and infect the fetus. It is true that antibodies are able to cross the placenta, but only specific ones (IgG1 and IgG3) and these take time to make in the mother after primary infection. This lag phase required to make IgG antibodies gives the virus sufficient time to infect and replicate in the embryo.

I believe that when you are hitting something hard and make a hard fist, you can cause extensive strain on your wrist and can tear ligaments, which take longer to heal, which is why the gloves prevent you from making a full fist. Also, several factors may be to blame for boxers broken arm. Perhaps the wrist is not designed to withstand such a great force of impact so that when even there is a slight twist or angle during impact, the bone just breaks.

Can you be a little more specific because it really depends on which protein you are talking about (ie. nNos, eNos, iNos) that forms NO resulting in oxidative toxicity. I also don't think that FAS ligand and FAS intteraction is actually blocked by NO since both are trying to initiate programmed cell death (apoptosis). NO is harmful for the cell and its production results in intracellular degradation and FAS pathway recruits in death domains that initiate a nuclease that is able to enter the nucleus and cleave DNA.