macarena
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Tough time brominating quite a basic ketone
macarena replied to fireoncells's topic in Organic Chemistry
Hi there ! Try to brominate using DMF as a solvent and TsOH as a catalyst (Lewis acids such as anhydrous ZnCl2 might also work). Succinimide is easily soluble in cold water so you should be able to separate it from your haloketone. There might also be an option to block the Py nitrogen but I think that is just too complicated. Hope you got something out of it.