If Avandia has been working to control your diabetes, but you are concerned about the possible cardiovascular side effects talk to your physician about another thiazoliadinedione (Avandia's drug class): Actos (pioglitazone).
Studies have shown pioglitazone does not increase incidence of mortality in patients. As a scientist researching pioglitazone, I have found that cardiomegaly was seen in one strain of rodent, however, we did not evaluate cardiophysiology in these animals.
That aside, meta-analyses do not show an increased risk of mortality.
Most importantly ASK YOUR PHYSICIAN!