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Which of the following best explains variable expression in mitochondrial diseases? a. locus heterogeneity b. heterozygosity c. heteroplasmy d. modifier locie. imprintingts for a homework from genetics... If anyone knows the right answer pls write with a short explanation Thanks! I am personally confused because i dont know how to think. If we take for a cause of diseases only changes in mtDNA i would say C for an answer. But mitochondrial proteins and their function is also under nuclear DNA. Please help!