Dude

It was not my intent to be insulting. Clearly there is no controversy over the structure/sequence of tRNA. I find the assertion made in the op/title a little odd though, even for a non native English speaker.

I'm sorry that you seem to have comprehension problems. Perhaps you could go back and read the title of this thread once more, before you emberrass yourself further.

Is English not your primary language? I only ask because your post is practically incoherent. I'm not trying to insult you, just saying that it is difficult to decipher what you are saying/asking. Yes, the T arm of tRNA has thymine. Are you asking why this is the case? It seems, from your first post in the thread, that you already have some wild speculation about "controversy". What controversy?

It depends on the disease. PKU, for example, can be controlled by diet. Cyctic fibrosis, on the other hand, means you are not going to enjoy a long life. What specific genetic disease are you asking about Voltman?