rosetyler

Hi! There is no explanation about mitochondrial DNA replication in my biochemistry textbooks so I searched the internet and found a few articles but I'm not sure if I understand it correctly. Can anyone help? So the heavy strand is synthesized as the leading strand and the light strand as the lagging strand? Their origins are separated on the chromosome and the heavy strand origin is in the noncoding sequences and the light strand origin is close to tRNA genes. Why? And there are RNA primers involved as well, right? Thank you!

Thanks for the answer! But I then realized that the increased amplitude because of the stimulus meant the increased amplitude for the entire n. ischiadicus and not only one neuron. So problem solved!

Hi! In our physiology class, we were working with the Simnerv program, where you experiment with the n. ischiadicus of a frog. In the first experiment, we were stimulating the nerve with different amplitudes: 20, 40, 60 ... mV. The amplitude of the action potential was increasing with the greater amplitude of the stimulus. My question is why? Isn't it so that the amplitude of the action potential is not dependent on the amplitude of the stimulus? That it's all-or-nothing? My second question is why do we need two stimulating and two recording electrodes on the nerve? Isn't one of each enough? I imagine that you put one stimulating electrode on one end of the nerve and activate it, and the signal gets to the other end of the nerve where the recording electrode is. Am I being too simplistic? And why does the shape of the AP change if we change the distance between the electrodes? Thank you!