

CharonY
Moderators-
Posts
13394 -
Joined
-
Last visited
-
Days Won
154
Everything posted by CharonY
-
Prove the negative of the Monty Hall problem
CharonY replied to TakenItSeriously's topic in Brain Teasers and Puzzles
I am not sure why there are spoiler tags as there are only a number of assertions and handwaving, but I cannot see any actual data/hints, references or relevant information. -
Well the few times I got stopped the officer did not even flinch when I reached into the glove compartment to get my registration and insurance papers. So I do not think that following orders is the only thing that matters. Fear, yes. But why and why are there marked differences (and among which lines ?).
-
On a broader scale one has to remember that the TCA cycle is the central of metabolism, i.e. a lot of conversion from one class of metabolites passes through the cycle. As a corollary there are many bypasses that flow in and out of the TCA cycle. Hence changes withing the cycle can have quite broad effects on many metabolite pools and, as already mentioned, the cycle is not, well, linear. There are single-step reactions which can have similar effects as OP outlines, but there are various branches that can be used to bypass a defective enzyme (to a certain degree). Finally, one should add that it is also dependent on the organisms, as especially prokaryotes have massive variability when it comes to how the TCA cycle is formed and what bypasses it can use under varying conditions.
-
Prove the negative of the Monty Hall problem
CharonY replied to TakenItSeriously's topic in Brain Teasers and Puzzles
Because they dismiss the additional info that the host reveals a wrong door and instead and instead reduce the question to a two door problem. I.e. it is assumed that the reveal simply removes it out of the equation, whereas as others pointed out it is still very much part of it. -
Prove the negative of the Monty Hall problem
CharonY replied to TakenItSeriously's topic in Brain Teasers and Puzzles
I am still not entirely sure what your question is, but the 50:50 appears to be intuitively correct (whilst being wrong) as people generally dismiss the additional information provided by revealing one wrong door. Edit: crossposted -
I would have to dig a bit, but IIRC there is the often-assumed rational choice model of criminal action, which is a simplified model assuming that crimes are conducted as the result of a rational decision process. However, studies coming from the cognitive science side call this model into question (see Wortley R. (2013). “Rational choice and offender decision making: lessons from the cognitive sciences,” in Cognition and Crime: Offender Decision Making and Script Analysis, eds Leclerc B., Wortley R., editors. (London: Routledge; ), 237–251). And this does not only apply to drugs because in truth, much of our everyday decision making (criminal or not) does not follow rational roles, which has been evidenced in numerous experiments.
-
There is a body of evidence that criminal behaviour is not based on rational decision making. For example, many studies have shown that stronger punishments do not work well as stronger deterrents. In case of burglaries there is actually data available (though not much). But it appears that there is no real evidence that shows that it works as a deterrent, either (actually, one of the effects is that guns are getting stolen...). Example
-
It does not have to be just a firearm control or just a mentality issue. Countries with high prevalence of guns still have lower firearm accidents and homicide rates than the US. In the UK or in many other parts of Europe a burglary is not associated with violence, hence people are more willing to just hide or leave the house rather than take a confrontational stance. I.e. people are more willing to leave violent actions to the authorities who, in many cases. have more training than many of their US counterparts. In very isolated areas self defense may be more tricky, yet crime rates are also typically lower than in urban centres.
-
Will a full brain scanner be invented in the next 50 years?
CharonY replied to fredreload's topic in Speculations
Precisely. It even uses another proxy, i.e. blood flow as measure of neuronal activity. If you really measured ion flow on that scale you would end up with huge, non-interpretable data dumps as the changes are locally often not massive. Then we also got EEG, MEG, SPECT and so on. But as mentioned, and what you may now realize is that the overall activity is the important bit, not the tracking of individual molecules. Hence, there is no need (or use) of molecular resolution. -
My guess is Adinolfi, Italian MEP, member of the 5 Stars movement (populist, eurosceptic, but not really right-wing), and EFDD, to which UKIP in the EU parliament also belongs. And probably a yes on the shallow part .
-
Photosynthesis is a somewhat later development. The point is not really the acquisition of hydrogen per se, but essentially liberation of electrons (or reducing equivalents) for energy conservation. Chemolithotrophy basically covers these range of oxidative processes. Of note, many, but not all chemolithotrophs are also extremophiles. Forgot to add: because of this process, some bacteria (hydrogen oxidizers) can utilize hydrogen as an electron donor.
-
Only the actual synthesis of the DNA is from scratch (using a very simple de novo/amplification chemistry). The genome sequence is from the same bacteria, with a portion of it removed. It is similar to very old studies to cure sequences, except that they now removed the whole chromosome and put in the synthesized ones. And yes, they basically took the cells, removed the DNA and put in the reduced version. I.e. it is still to early to call that an organism from scratch (and yes, the press has massively sold the technical and especially the scientific achievement).
-
But they were introduced into the same cell from the sequences were previously removed from.
-
Isn't it great for single-issue parties? Just burn and run. And come back when there is another crisis. Being part of the problem is so much easier than being part of the solution. Ironically, isn't he to remain in the EU parliament for a while?
-
Will a full brain scanner be invented in the next 50 years?
CharonY replied to fredreload's topic in Speculations
Basically the issue is that in order to understand functions we need a larger picture of brain activities. Looking at individual cells or even molecules is only relevant if we want to figure out specific biochemical activities and interaction, but are not too interested in overall physiology. There is no easy way to bridge this particular gap. To put it differently, different resolution is used for different questions. If you want to look at brain activity you need something more like PET, MRI or equivalent and improved versions thereof. If want to go into high-resolution stuff once you are interested in cellular physiology or biochemical interactions. -
Will a full brain scanner be invented in the next 50 years?
CharonY replied to fredreload's topic in Speculations
So do you look at the leakage and pressure or at individual water molecules? -
Will a full brain scanner be invented in the next 50 years?
CharonY replied to fredreload's topic in Speculations
In order to figure out where water flows in a system (even a small one) would you try to measure individual water molecules? -
You see, the issue that I see or the disappointment that I have does not stem from the immediate economic ramifications. Rather, there is a whole range connected to the Brexit vote. 1) people can be easily manipulated to vote against their interest without any shred of evidence and by exclusively appealing to feels 2) the results and aftermath basically demonstrated that a sizable portion of the population are not "concerned citizens" but outright xenophobes and bigots (as a corollary, it also shows that even if one removed all visible minorities chances are that some other scapegoat is found) 3) while this mainly shows the because of that, we see legitimization of extreme right-wing "policies" which do not need a foundation in reality to be successful 4) we have seen that behavior more than a couple of times throughout recent as well as not so recent history. The only thing we do learn from this is obviously that we don't. I could add more to that, but it is just overall depressing.
-
Program to see 3D tertiary protein strucutre?
CharonY replied to Elite Engineer's topic in Biochemistry and Molecular Biology
3D structures are typically based on crystallographic studies and are highly complex you can see and download structures form the PDB database. Not all structures are of sufficient resolution as the most common distance between a hydrogen and the acceptor in a given pair is usually below 2.5 angstrom. That being said, even a lower resolution structure can provide clues which and where certain moieties interact. In any case these are not trivial to understand. -
Will a full brain scanner be invented in the next 50 years?
CharonY replied to fredreload's topic in Speculations
You are switching between several orders of magnitude between and even within a sentence. Again what would a molecular resolution really tell you? Remind more again on wich scales neuronal connections are formed. Also try to visualize the change from tissue to cell, subcellular compartments, macromolecules, ions and atomic structure. -
Ultracentrifuge vs. centrifuge for membrane separation
CharonY replied to allaroundanonymous's topic in Biology
If the force of the same, i.e. you do not need the higher forces of an ultracentrifuge it should not matter. What could make a difference is if you have different vials. -
I am registered cynic, so it should not surprise me in the least. But I still feel a pang of disappointment seeing these things happening.
-
On a different note, it is sad to see that the vote has empowered racists and bigots to come of the woodwork, as they assume that after they had their say it is now socially acceptable. Obviously, it only shows that these thoughts are bubbling under the surface of virtually all societies (easily seen with refugee crisis in other European countries). Still, sad to see that in action. Also noteworthy is that this time the resentments are not exclusively against the obvious targets (i.e. visible minorities) but also increased insults and abused have been targeted against especially Polish (and other European) communities. I should stress that this is not exclusively directed against Brits, I have nothing against them, and some of them are my best friends (OK I could not stop myself, sorry). Rather, it shows how very primitive, almost tribal notions persists even in very modern societies that are well covered up under a veneer of civility. However, once there is even a nudge that implies that this behaviour is acceptable it tends to break out to expose the ugly, hate-filled underbelly of society. We are just deluding ourselves thinking that we are better and have overcome these issues. We (as the whole society) really have not. Edit: Also, it is telling that UKIP got the popular vote for the EU-parliament, which is just mind-boggling. And as it turns out they are also the "laziest party" In that regard Farange's speech is set to destroy any irony meters vaguely pointed in his direction. I am serious, especially listen to the end of the speech where he demands that the EU does not cut its nose to spite its face and tells them to be sensible grown-ups... after telling the MEP that they never had a proper job in their lives...
-
Apart from the fact that this is a two-year old thread, it should be added that neither ELISA nor Western are exclusively used to measure antibodies. In fact they can (and often are) used to quantify anything that can be a antigen, including proteins other than immunoglobulins, peptides, hormones as well as other immunogenic biomolecules.