A regular woman usually has two X cromossomes, one of them is inactivated. Why does the Turner's Syndrome and the Klinefelter Syndrome leads to mental retardation? If, apparently, only one X cromossome is necessary, then why is it such a severe condition when you have Turner's Syndrome? Or if someone has 3 X cromossomes, why can't be 2 X cromossomes inactivated?
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