nec209

Why is not all drugs are specific target ? Is that not the holy grail of target drugs? Of hopes in the future to find target chemotherapy that only binds to that protein?

If I understand drugs are small molecules that activates or inhibits target proteins and results in a therapeutic benefit to the patien.So why do drugs have side effects? Drug is small molecules that are shape of proteins of they interact and therefore will bind to it.So why are there side effects? May be I'm confusing the future of target drugs with how drugs work? One of the main problem with diseasees , illnesses and Chemotherapy is side effects. And if I understand it is easy to make drugs , but very hard to make drugs that don't have side effects. That take cancer for example , it is easy to come up with chemotherapy !!! But very hard to come up up with chemotherapy that works but does not kill you or make you very ill. What all this talk of target drugs in future that only bind to the protein.

Any thing I read is Combustion also known as burning is chemical reactions between fuel and an oxidant accompanie combustion reaction, a compound reacts with an oxidizing element, such as oxygen or fluorine and the products are compounds of each element in the fuel with the oxidizing element. I think what I'm not understanding is oxidant and why oxygen or fluorine only thing thing that will allow burning.I think I may be confusing it with rockets has in space there is no oxygen so how does it work. Looking up what is Fuels (Fuels are any materials that store potential energy in forms that can be practicably released and used for work) only show three types chemical energy that could be released through combustion , nuclear energy (via nuclear fission or nuclear fusion or cellular biology process known as cellular respiration.And chemical energy or cellular biology need oxygen for it to work.I gusess I'm confused why it only works with oxygen and confusing it with space rockets. Also I think I may be not fully understanding how internal combustion engine work.I know internal combustion engine is an engine in which the combustion of a fuel occurs with an oxidizer ( air) in a combustion chamber.Again internal combustion engines depend on combustion of a chemical fuel with oxygen from the air. Cars and airplanes are air-breathers reactants need to oxidize in air.So it seems fuels burn easier than other fuels because they combine with oxygen better. So if there was no oxygen tha cars or airplanes would not work , it would have to carry its own oxygen tank for burning of fuel to work. Or other way saying it for internal combustion engine to work need oxygen. I think I'm confuing it with rocket engines and why oxygen is needed.Why burning of fuel does not work with out oxygen. Some fuels burn easier than other fuels because they combine with oxygen better.But why oxygen is needed. Any other ways for fuels burn wit out oxygen.

And the more energy it has? I think what I'm confused is understanding why some fuel sources have more energy than other fuel sources.Why some fuel sources are just not practical. Where does the energy come from.Is it releasing the electrons in the atom or the density? That look at space rocket it takes fuel to launch a mass into space but the fuel itself has mass its a bit of a problem. That's why current rockets are multi-stage clamber to reach orbit. The fuel packs just enough of a punch to make the trip at all. A rocket 90% of it is fuel just to take up 5% to 10% of payload. From what I understand the fuel rockets uses is the most densely packed fuel. Same with cars and airplanes very costly and not fuel efficient. That why I said they need to find other fuel source.But I'm not understanding the chemistry of this.Why some fuel sources are better than other fuel sources.Why some fuel sources are just not practical.Some fuel sources have more energy than other fuel sources. Why the fuel sources they are using now is not fuel efficient.They have to find other fuel source that is more fuel efficient.

I thought more densely packed molecules more energy output and more fual efficient.Where less densely packed molecules less energy output and less fual efficient. I said the problem is fuel they are using and they have to find other fuel source that has more energy thus more fual efficient. example possible to get cars to run on other fuel sources other than fossil fuels that has more energy thus more fual efficient.

Why are some fuel sources better than other fuel sources? I mean some things are better fuel sources than other fuel sources.Some things burn easy and other things do not. Some fuel sources have more energy than other fuel sources.Where has other fuel sources have less energy example it hard to get car to run on water ,oxygen or helium and yet other fuel sources like wood or fossil fuels very easy and have lots more energy.

We still don't know why people are getting cancer and autoimmune diseases. And why it getting so out of control now. Some theories are bad food ,junk food ,chemicals in food ,being fat and obesity and type of foods people have.But science still can't explain the why and how. What is it in the food. What in the foods that trigger it. What is it about the food.

Looking at the stats 1/2 people who have cancer will die. http://www.cancerresearchuk.org/cancer-help/about-cancer/cancer-questions/what-percentage-of-people-with-cancer-are-cured About 40% of people will get cancer in there life time.This treatment you talk about sounds very new and probably does not work will all types of cancers out there.

I know 5 friends this year that died with cancer !! Also when the NDP leader Jack Layton in Canada died with cancer and rich man like Steve Jobs and man like Patrick Swayze that leaves you in shock how primitive the health care is. Also disease like motor neuron disease , amyotrophic lateral sclerosis (ALS) ,MS, Parkinson's, strokes or spinal cord injury and disease like HiV and autoimmune diseases. All despite many drugs and vaccines in the late 19 century and early 20th century using a blindfold approach in baement of your home lab.All these fancy powerful computers and better understanding of the human body and chemistry and nice state of the art lab with army of chemists and scientists working on the problem. With little drugs coming out there now. I hear three theories explaining slow down. 1.government retriction , once a chemists finds a computer model that shows results and you doctor prescribes medication add 10 to 15 years to it.Alll running lab rats tests ,clinical trials and testing. You wont it faster , have people sign up for guinea pigs and lower the testing and you will get 5 year mark than 10 to 15 year mark. 2.The easy diseases have cure and now on to the hard to cure diseases. 3.pharmaceutical incentive conspiracy. More profit making dugs to finght problems they know and easer than speding millions dollars on mystery diseases they don't know hoe to cure.

Why does the human immune system not destroy it? Can the human immune system pick out cancer cells vs normal cells. Do cancer cells have markers on them that the immune system or drugs not target them. I read about target drugs in the future.

I believe the liver is best at it.But your heart or brain cannot.Even small brain damagae or small damage to the heart the body cannot repair it self same with the spine.

Why are some cancers have much higher cancer survival rate than other types of cancers?What types cancers have higher survival rate than other types of cancers. Looking at this http://2.bp.blogspot.com/-Yn1crn6Gpak/T476j27qtQI/AAAAAAAAAz4/NhkYXSVFGBs/s1600/Survival+Rate+by+Cancer+Type.png Looking at it Pancreas ,Liver,Bile duct ,Esohagus ,Lungs ,Bronchus ,Stomic ,Mutiple Myeloma ,Brain and Leukemia have very bad survival rate. http://2.bp.blogspot.com/-Yn1crn6Gpak/T476j27qtQI/AAAAAAAAAz4/NhkYXSVFGBs/s1600/Survival+Rate+by+Cancer+Type.png http://avondaleassetmanagement.blogspot.ca/2012_04_01_archive.html Why is it hard to make drugs to fight of the cancer?

There was artical I was reading that they are not happy with the Higgs becuse they say it does not answer all of the quections . I will see if I can find that artical.

It looks like spiders are getting bigger now and webs are getting bigger too.This is not good becuse it changes the ecosystem if spiders become more of predator .

The artical does not say if thought is communicated by telepathy.So they till don't know what is be communicated by telepathy.

How long before 4D printing and molecular assembler take of? Would you say 10 or 15 years out? What are they using 4D printing and molecular assembler now? I can't seem to get much information on this.The only thing I can find is this. http://allthingsd.com/20130226/from-ted-the-future-of-robots-4d-printing-personalization-and-adaptation/?refcat=news What would 4D printing be used for? Team of scientists in Toronto Canada are doing that now. http://www.torontosun.com/2013/02/28/4d-printing-lets-objects-build-themselves

The prospect of mind-reading technology has moved a step closer after scientists established the first brain-to-brain connection. Using electrodes implanted in the brains of two rats, one rodent was able to pass information to another in a cage thousands of miles away – albeit without knowing it was doing so. The experiment, by researchers from Duke University in North Carolina, is the first direct communication link between two minds. Previous studies had shown that visual and tactile information could be transferred between a brain and a computer, for example allowing amputees to control prosthetic limbs, but the latest research represents a significant advance. Although the connection was extremely basic, it raises the prospect of more complex devices that could one day allow people to read each other’s minds. Read more here http://news.nationalpost.com/2013/02/28/telepathy-closer-to-becoming-reality-after-rats-brains-linked-across-continents/

What accent is this? http://www.youtube.com/watch?v=9veMud_L3eE Note I don't hear any drawl here like you where saying. Also note the volume is turn way down on this clip.

Would this be called a southern US accent ? http://www.youtube.com/watch?v=tjB1JaeYY9A&feature=player_embedded Note she is from the UK trying it.

What is happing is doctors are giving out antibiotics like candy and what is happing is the antibiotics are killing the good germs that fight off the bad germs and now we got bad germs that are hard to kill .So now they have to find new antibiotics to kill these new germs that would not be problem with good germs has they would kill it.

I hear people say some times he or she has a southern US accent ..So I'm trying to understand what makes the southern US accent stand out.People say in southern US accent they talk slow and have deeper voice . Also anyone know any movies with female or male with southern US accent that may help me understand what the southern US accent sounds like?

Why hot topic like anti-gravity ,wormholes ,warp drive ,levatation is like asking cave man explain logic gates works and CPU . That is why know one has even pip dream idea on board on even if this real or not or even going about this on to see if this can even be real.

How can drug companies mess up in such modern times? With such modern times how can this happan? http://o.canada.com/2012/09/01/bc-germany-thalidomide-update-1-tv/

What are target drugs or gene therapy that doctors are working in the future use for cancer and other diseases? I hear talk of hope in the future that target drugs or gene therapy may be used for cancer and other diseases

Read about here http://www.inews880.com/Channels/Reg/CyberCorner/Story.aspx?ID=1660595 I have 3 questions 1.How will space mining be profitable when going into space is so costly ? 2. Putting people or payload in space is extremely costly 3.How are they going to get in space go to China or Russia? ( NASA does not put people or payload in space any more ).