thankududes Posted October 26, 2016 Posted October 26, 2016 Hey, if I start a titration of Histidine at the pKa of the N-terminus (pH of 9.1) with HCl, where would the first equivalence point be? I was thinking that the 1st equivalence point would be between 9.1 and 6.0 (pI) however mols of buffer would not equal mols of acid until the pka of 6.0 is reached. On the titration curve I must label where this equivalence point is but I have never started a titration at a pka before, can someone please help? thank you!
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