Signal Sequence Animation

[Claris]

Hey guys,

 

I am doing an animation about the synthesis of proteins on ER.

Remember the moment when Signal Sequence is cut off by Signal peptidase and leaves the translocon?

So, I animated it going into the lipophilic part of the membrane (oriented horizontally), but then noticed that all images show it oriented vertically (see attachment).

Isn't it supposed to be lipophilic? What would be the most correct way to orient it inside the lipid bilayer?

Thank you for your time!