Structure of Aspirin

[Kandi]

Hi! I'm confused about which Hydrogen on the aspirin structure ionizes to make aspirin a monoprotic acid? Thanks!!!

[budullewraagh]

it's the one bonded to the oxygen in the carboxyl group

[Kandi]

Thanks!!!

[Sarahisme]

lol, this is along shot, but Kandi or budullewraagh you wouldnt happen to know the answer to this...

 

http://38.118.74.97/forums/showthread.php?p=172871#post172871

 

??

 

Thanks

 

Sarah

[Ophiolite]

Sarah, my organic chemistry is some distance in the past: I don't know if this will be of any help to you. My battered copy of Feiser and Feiser assures me that formation of salicylic acid by Scmitt's modified Kolbe process occurs "in close to the theoretical ampunt"; that it (the Kolbe process) when applied to other phenols usually proceeds in good yield"; and that the acetyl derivative (aspirin) can be prepared efficiently.

These vague, qualitative remarks do, nevertheless, suggest your achieved yield may not be unreasonable.

Good luck.

[Sarahisme]

oh ok, thats really good, thanks for that