Could you survive with four copies of the X chromosome? Would your life be any different?

[medgenomeclaria]

Can anyone answer it as soon as possible? Let me know more about genetics.

[Rahaman]

It is rare but possible to have up to 4 copies of X chromosome in the genetic make up of an individual.

This is called Multiple X syndrome in female (such female are usually called meta or super females) and Klinefelter syndrome in male.

In both circumstances, individual can live since the condition is not lethal. However, males of such condition are often sterile and produce low amount of testosterone while females are often tall and fertile.

[John S]

People can survive with multiple copies of the X chromosome, although they usually have delayed cognitive development and reproductive abnormalities, among other symptoms. The larger the number of extra copies of the chromosome there are, the more severe the symptoms are. There have been cases of males born with as many as five copies of the X chromosome. In this case, their karyotype would be 50, XXXXXY.

Edited September 17, 2017 by John S