Gene therapy and its connection to evolution

[cyber_indian]

You pretty much got it, can be said in your words too. But I prefer it like this:

 

"In order to survive after the Earth is destroyed, we must find other suitable worlds and send out bacteria. These bacteria must be able to create a new biosphere suitable for the ecosystem that must be deployed by them, so our existence can continue in time and space."

 

Those memory bacteria may not exist nowadays because there is not purpose of them anymore, but I don’t mean it can't be done. We also may not have enough understanding of genetics yet. Anyway it's like writing in assembler language - at first it might seems impossible, but once you master the subject it's mostly work than philosophy. And even having metabolic load as an obstacle - we can always go around it. About putting the entire ecosystem all together - what we do is catalogue all species and as you said "there is 17% differences between us and yeast" (as far as I also remember it was in percents close to what you said) we put only gene difference in that "memory pool".

 

P.S. there is a little update:

 

Scenario 1 - memory units:

-A blueprint - all the life form's DNA of the previous world ecosystem gathered and reduced it to greatest common factors (example for that is vertebrates - head, body, arms/wings/fins, legs and tail), strategically planned and stored in bacteria as gene module (group of genes working together to fulfill a function) units.

-A way to keep gene modules stored and suppressed until transplanted (memory bacteria doesn’t transcode these extra genes – probably condense that extra chromosome).

-A transplanting tool – vector (virus).

-And a way the transplanting tool to identify only the target specie and specific type of cell (antigen/antibody mechanism).

At first bacteria secrets a blank virus (a virus with DNA for its own structure only), by infecting a memory bacterium it multiplies and charging itself with the designated gene modules and antigens (a process called “transduction”). Now because of the antigen/antibody mechanism the virus is targeted to fuse/append (new DNA information) only with a specific specie and tissue.

 

Scenario 2 - prophage:

-A blueprint - all the life form's DNA of the previous world ecosystem gathered and reduced it to greatest common factors (example for that is vertebrates - head, body, arms/wings/fins, legs and tail), strategically planned and stored in bacteria as gene module (group of genes working together to fulfill a function) units.

-Prophage with attached gene modules in bacterium host.

-A triggering factor for the phage (virus).

-And a way the phage tool to identify only the target specie and specific type of cell (antigen/antibody mechanism).

[Deathby]

No, that was 17 changes (not %, just alterations in sequence) in a single GENE. And there are millions of genes, you can't just narrow it down to, oh yeah all those groups have the "vertebrate gene" and those groups have the "head gene" because it isn't a single gene, its hundreds of genes, all of which are radically different even between fish and amphibians.

 

It'll be possible to inject DNA into your bacterium (we can already do it- in little snippets), but humans have 21 chromosomes worth of DNA and bacteria only have a single DNA. You're loading them with 2100% more genetic material than they had before- its simply not going to fit, and if it does it will be weighed down by it. Even compressed human DNA (without all the junk DNA) will overload a bacterium, you won't be able to fit millions of species' worth of DNA into a single bacterium.

[cyber_indian]

One storage will be fit with one unit (consisting of small number of closely working genes), of course you can't fit a whole genome. Because bacteria are small, we don't need to bother how many storage cells we can have. And because we can target the units (with the help of antigen/antibody) we don't bother that they are mixed up together.

 

About "vertebrate gene" what we do is just put the most common gene and later after it's been deployed, the universal mechanism (for appending the genome and molding specie functionality - called natural selection) will fit the gene for specie's best shape and use.

 

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