Azur Posted August 23, 2017 Posted August 23, 2017 I was annotating mitochondrial genomes, and it dawned on me that all the mitochondrial protein coding genes except CytB have a terminal stop codon. Cytochrome b instead ends on a lone T, and the TAA stop codon is completed by the addition of 3' A residues to the mRNA. But why? Why is CytB different?
Endy0816 Posted August 23, 2017 Posted August 23, 2017 I was reading it can cleave off the following tRNA. Some people do have a mutant form with a stop codon causing excercise exhaustion.
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