Yanis_Fr Posted January 11, 2018 Posted January 11, 2018 Hello! I have a question and I have no idea of the answer. Could you help? A negative RNA enveloped virus, extremely pathogenic for humans, has recently been discovered. Its pathogenicity is caused by a total inhibition of the type I interferon response by two viral proteins: the capsid protein and the RNA dependent RNA polymerase. On the other hand, the adaptive response is quite competent. Which of the following vaccine strategies (attenuated viruses, DNA, recombinant proteins, viral pseudo particles, retro or lentiviral vectors) would be the most appropriate to protect the population against this virus and which would be as dangerous as the virus itself and why? Thanks a lot for your help!
zapatos Posted January 14, 2018 Posted January 14, 2018 What is the virus you are referring to? Do you have a link? Thanks.
Yanis_Fr Posted January 14, 2018 Author Posted January 14, 2018 Hi, thanks for your reply! I don't have any other information about the virus
CharonY Posted January 28, 2018 Posted January 28, 2018 This sounds like homework. Think about what immune responses are triggered by which strategy.
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