Acetaminophen Use for Fever in Children Associated with Autism Spectrum Disorder

[Strange]

5 minutes ago, ritastrakosha said:

He is a scientist.

No he isn't. He is a fraud who faked results.

Quote

He discovered very interesting things and he had minor procedural problems with his research. 

He didn't discover them. He invented them. Falsified results obtained by unethical means, including the abuse of children with developmental problems, are not "minor procedural problems".

 

[Phi for All]

5 hours ago, ritastrakosha said:

Your concern is the credibility of medicine, my concern is the life of my children.

Vaccinations are, by definition, much more about populations and can't afford to be selfish and subjective.

 

5 hours ago, ritastrakosha said:

Do you care for the life of millions of children? If yes, the credibility of medicine is of minor importance.

Are you serious with this?! If people can't trust doctors because of your bullshit fear and ignorance program, how many will die because they didn't seek medical help? You're using Misleading Vividness as a fallacious argument regarding children, when the real damage is being done by you and others like you, killing children every day with your vaccination hoaxes.

[CharonY]

Also note that after Wakefield many folks looked into the link and if one does not cherry pick or falsify data, the association vanishes. Meanwhile, lack of immunization has brought back diseases that were on the brink of vanishing, and children pay the price for that. 

[ritastrakosha]

Wakefield found that children got autism after getting vaccinated and that they had colon inflammation.

Let's see what some newer studies say:

Pilot comparative study on the health of vaccinated and unvaccinated 6-to 12-year-old U.S. children

https://www.researchgate.net/publication/317086531_Pilot_comparative_study_on_the_health_of_vaccinated_and_unvaccinated_6-to_12-year-old_US_children

Vaccinations have prevented millions of infectious illnesses, hospitalizations and deaths among U.S. children, yet the long-term health outcomes of the vaccination schedule remain uncertain. Studies have been recommended by the U.S. Institute of Medicine to address this question. This study aimed 1) to compare vaccinated and unvaccinated children on a broad range of health outcomes, and 2) to determine whether an association found between vaccination and neurodevelopmental disorders (NDD), if any, remained significant after adjustment for other measured factors. A cross-sectional study of mothers of children educated at home was carried out in collaboration with homeschool organizations in four U.S. states: Florida, Louisiana, Mississippi and Oregon. Mothers were asked to complete an anonymous online questionnaire on their 6-to 12-year-old biological children with respect to pregnancy-related factors, birth history, vaccinations, physician-diagnosed illnesses, medications used, and health services. NDD, a derived diagnostic measure, was defined as having one or more of the following three closely-related diagnoses: a learning disability, Attention Deficient Hyperactivity Disorder, and Autism Spectrum Disorder. A convenience sample of 666 children was obtained, of which 261 (39%) were unvaccinated. The vaccinated were less likely than the unvaccinated to have been diagnosed with chickenpox and pertussis, but more likely to have been diagnosed with pneumonia, otitis media, allergies and NDD. After adjustment, vaccination, male gender, and preterm birth remained significantly associated with NDD. However, in a final adjusted model with interaction, vaccination but not preterm birth remained associated with NDD, while the interaction of preterm birth and vaccination was associated with a 6.6-fold increased odds of NDD (95% CI: 2.8, 15.5). In conclusion, vaccinated homeschool children were found to have a higher rate of allergies and NDD than unvaccinated homeschool children. While vaccination remained significantly associated with NDD after controlling for other factors, preterm birth coupled with vaccination was associated with an apparent synergistic increase in the odds of NDD. Further research involving larger, independent samples and stronger research designs is needed to verify and understand these unexpected findings in order to optimize the impact of vaccines on children's health.

Aluminium in brain tissue in autism [vaccines have a lot of aluminium]

Author links open overlay panelMatthewMold^aDorcasUmar^bAndrewKing^cChristopherExley^a

Show more

https://doi.org/10.1016/j.jtemb.2017.11.012Get rights and content

Under a Creative Commons license

open access

  Abstract

Autism spectrum disorder is a neurodevelopmental disorder of unknown aetiology. It is suggested to involve both genetic susceptibility and environmental factors including in the latter environmental toxins. Human exposure to the environmental toxin aluminium has been linked, if tentatively, to autism spectrum disorder. Herein we have used transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminium content of brain tissue from donors with a diagnosis of autism. We have also used an aluminium-selective fluor to identify aluminium in brain tissue using fluorescence microscopy. The aluminium content of brain tissue in autism was consistently high. The mean (standard deviation) aluminium content across all 5 individuals for each lobewere 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) μg/g dry wt. for the occipital, frontal, temporal and parietal lobes respectively. These are some of the highest values for aluminium in human brain tissue yet recorded and one has to question why, for example, the aluminium content of the occipital lobe of a 15 year old boy would be 8.74 (11.59) μg/g dry wt.? Aluminium-selective fluorescence microscopy was used to identify aluminium in brain tissue in 10 donors. While aluminium was imaged associated with neurones it appeared to be present intracellularly in microglia-like cells and other inflammatory non-neuronal cells in the meninges, vasculature, grey and white matter. The pre-eminence of intracellular aluminium associated with non-neuronal cells was a standout observation in autism brain tissue and may offer clues as to both the origin of the brain aluminium as well as a putative role in autism spectrum disorder.

J Autism Dev Disord. 2018 May;48(5):1523-1529. doi: 10.1007/s10803-017-3409-5.

Association of Autism Spectrum Disorders and Inflammatory Bowel Disease.

Lee M^1,2,3, Krishnamurthy J⁴, Susi A⁴, Sullivan C⁴, Gorman GH⁴, Hisle-Gorman E⁴, Erdie-Lalena CR⁴, Nylund CM⁴.

Author information

Abstract

Autism spectrum disorders (ASD) and inflammatory bowel disease (IBD) both have multifactorial pathogenesis with an increasing number of studies demonstrating gut-brain associations. We aim to examine the association between ASD and IBD using strict classification criteria for IBD. We conducted a retrospective case-cohort study using records from the Military Health System database with IBD defined as having one encounter with an ICD-9-CM diagnostic code for IBD and at least one outpatient prescription dispensed for a medication to treat IBD. Children with ASD were more likely to meet criteria for Crohn's disease (CD) and Ulcerative colitis (UC) compared to controls. This higher prevalence of CD and UC in children with ASD compared to controls confirms the association of ASD with IBD.

Eur J Pharmacol. 2016 May 5;778:96-102. doi: 10.1016/j.ejphar.2015.03.086. Epub 2015 May 1.

Mast cells, brain inflammation and autism.

Theoharides TC¹, Stewart JM², Panagiotidou S², Melamed I³.

Author information

Abstract

Increasing evidence indicates that brain inflammation is involved in the pathogenesis of neuropsychiatric diseases. Mast cells (MCs) are located perivascularly close to neurons and microglia, primarily in the leptomeninges, thalamus, hypothalamus and especially the median eminence. Corticotropin-releasing factor (CRF) is secreted from the hypothalamus under stress and, together with neurotensin (NT), can stimulate brain MCs to release inflammatory and neurotoxic mediators that disrupt the blood-brain barrier (BBB), stimulate microglia and cause focal inflammation. CRF and NT synergistically stimulate MCs and increase vascular permeability; these peptides can also induce each other׳s surface receptors on MCs leading to autocrine and paracrine effects. As a result, brain MCs may be involved in the pathogenesis of "brain fog," headaches, and autism spectrum disorders (ASDs), which worsen with stress. CRF and NT are significantly increased in serum of ASD children compared to normotypic controls further strengthening their role in the pathogenesis of autism. There are no clinically affective treatments for the core symptoms of ASDs, but pilot clinical trials using natural-antioxidant and anti-inflammatory molecules reported statistically significant benefit.

Vaccination and autoimmune diseases: is prevention of adverse health effects on the horizon?

Maria Vadalà,^1,2 Dimitri Poddighe,³ Carmen Laurino,^1,2 and Beniamino Palmieri^1,2

Author information Article notes Copyright and License information Disclaimer

Go to:

Abstract

Autoimmune diseases, including multiple sclerosis and type 1 diabetes mellitus, affect about 5% of the worldwide population. In the last decade, reports have accumulated on various autoimmune disorders, such as idiopathic thrombocytopenia purpura, myopericarditis, primary ovarian failure, and systemic lupus erythematosus (SLE), following vaccination. In this review, we discuss the possible underlying mechanisms of autoimmune reactions following vaccinations and review cases of autoimmune diseases that have been correlated with vaccination. Molecular mimicry and bystander activation are reported as possible mechanisms by which vaccines can cause autoimmune reactions. The individuals who might be susceptible to develop these reactions could be especially not only those with previous post-vaccination phenomena and those with allergies but also in individuals who are prone to develop autoimmune diseases, such as those with a family history of autoimmunity or with known autoantibodies, and the genetic predisposed individuals.

Further research is encouraged into the direct associations between vaccines and autoimmune conditions, and the biological mechanisms behind them.

Curr Opin Neurol. 2016 Jun;29(3):362-71. doi: 10.1097/WCO.0000000000000318.

Vaccine-associated inflammatory diseases of the central nervous system: from signals to causation.
Nguyen XH1, Saoudi A, Liblau RS.

Abstract

PURPOSE OF REVIEW:

As the most cost-effective intervention in preventive medicine and as a crucial element of any public health program, vaccination is used extensively with over 90% coverage in many countries. As approximately 5-8% of the population in developed countries suffer from an autoimmune disorder, people with an autoimmune disease are most likely to be exposed to some vaccines before or after the disease onset. In fact, a number of inflammatory disorders of the central nervous system have been associated with the administration of various vaccines. These adverse events, be they spurious associations or genuine reactions to the vaccine, may lead to difficulties in obtaining public trust in mass vaccination programs. There is, thus, an urgent need to understand whether vaccination triggers or enhances autoimmune responses.

RECENT FINDINGS:

By reviewing vaccine-associated inflammatory diseases of the central nervous system, this study describes the current knowledge on whether the safety signal was coincidental, as in the case of multiple sclerosis with several vaccines, or truly reflected a causal link, as in narcolepsy with cataplexy following pandemic H1N1 influenza virus vaccination.

SUMMARY:

The lessons learnt emphasize a central role of thorough, ideally prospective, epidemiological studies followed, if the signal is deemed plausible or real, by immunological investigations.

Autoimmune/Inflammatory Syndrome Induced by Adjuvants and Thyroid Autoimmunity

Abdulla Watad,^1,2,3 Paula David,^2,4 Stav Brown,³ and Yehuda Shoenfeld^2,3,5,*

Author information Article notes Copyright and License information Disclaimer

The autoimmune/inflammatory syndrome induced by adjuvants (ASIA), presented by Shoenfeld and Agmon-Levin in 2011, is an entity that incorporates diverse autoimmune conditions induced by the exposure to various adjuvants. Adjuvants are agents that entail the capability to induce immune reactions. Adjuvants are found in many vaccines and used mainly to increase the response to vaccination in the general population. Silicone has also been reported to be able to induce diverse immune reactions. Clinical cases and series of heterogeneous autoimmune conditions including systemic sclerosis, systemic lupus erythematosus, and rheumatoid arthritis have been reported to be induced by several adjuvants. However, only a small number of cases of autoimmune thyroid disorder have been included under the umbrella of ASIA syndrome. Indeed, clinical cases of Hashimoto’s thyroiditis and/or subacute thyroiditis were observed after the exposure to vaccines as well as silicone implantation. In our review, we aimed to summarize the current knowledge on ASIA syndrome presented as endocrinopathies, focusing on autoimmune thyroid disorders associated with the various adjuvants.

Keywords: autoimmune/inflammatory syndrome induced by adjuvants, thyroid, endocrinopathy, adjuvants, vaccines, silicone, Hashimoto’s thyroiditis, Graves disease

 

The autoimmune/inflammatory syndrome induced by adjuvants (ASIA)/Shoenfeld's syndrome: descriptive analysis of 300 patients from the international ASIA syndrome registry.

Watad A1,2, Quaresma M1,3, Bragazzi NL4, Cervera R5, Tervaert JWC6, Amital H1,2, Shoenfeld Y7,8,9.

Author information

Abstract

The autoimmune/inflammatory syndrome induced by adjuvants (ASIA) is a recently identified condition in which the exposure to an adjuvant leads to an aberrant autoimmune response. We aimed to summarize the results obtained from the ASIA syndrome registry up to December 2016, in a descriptive analysis of 300 cases of ASIA syndrome, with a focus on the adjuvants, the clinical manifestations, and the relationship with other autoimmune diseases. A Web-based registry, based on a multicenter international study, collected clinical and laboratory data in a form of a questionnaire applied to patients with ASIA syndrome. Experts in the disease validated all cases independently. A comparison study regarding type of adjuvants and differences in clinical and laboratory findings was performed. Three hundred patients were analyzed. The mean age at disease onset was 37 years, and the mean duration of time latency between adjuvant stimuli and development of autoimmune conditions was 16.8 months, ranging between 3 days to 5 years. Arthralgia, myalgia, and chronic fatigue were the most frequently reported symptoms. Eighty-nine percent of patients were also diagnosed with another defined rheumatic/autoimmune condition. The most frequent autoimmune disease related to ASIA syndrome was undifferentiated connective tissue disease (UCTD). ASIA syndrome is associated with a high incidence of UCTD and positive anti-nuclear antibodies (ANA) test. Clinical and laboratory features differ from the type of adjuvant used. These findings may contribute to an increased awareness of ASIA syndrome and help physicians to identify patients at a greater risk of autoimmune diseases following the exposure to vaccines and other adjuvants. The ASIA syndrome registry provides a useful tool to systematize this rare condition.

[Strange]

16 minutes ago, ritastrakosha said:

Wakefield found that children got autism after getting vaccinated and that they had colon inflammation.

No he didn't. He faked the results and lied about it. He is still lying about it. He made an entire movie to lie about it. And people like you believe him. 

16 minutes ago, ritastrakosha said:

Aluminium in brain tissue in autism [vaccines have a lot of aluminium]

No they don't. There is more aluminium in a cup of tea. 

You are obviously desperately searching for anything that will support your ridiculous beliefs.

 

[ritastrakosha]

3 hours ago, Strange said:

No he didn't. He faked the results and lied about it. He is still lying about it. He made an entire movie to lie about it. And people like you believe him. 

No they don't. There is more aluminium in a cup of tea. 

You are obviously desperately searching for anything that will support your ridiculous beliefs.

 

Studies published in scientific journals are not "anything". Can you bring references for "There is more aluminium in a cup of tea." statement?

[StringJunky]

6 minutes ago, ritastrakosha said:

Studies published in scientific journals are not "anything". Can you bring references for "There is more aluminium in a cup of tea." statement?

 

Quote

Aluminum is the third most abundant element after oxygen and silicon, and it is the most abundant metal, making up almost 9 percent of the earth's crust. Aluminum is found in plants, soil, water and air. Most plants have low quantities of aluminum, but a few are known to be aluminum accumulators, including some types of tea plants, grasses and orchids.

https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-ingredients/aluminum

Many vaccines with it in have up to a 0.5mg aluminium adjuvant.  Breast fed infants ingest about 7mg; 14  times what's in vaccines. If you want the list of Aluminium amounts in each vaccine click the link above.

[Strange]

2 minutes ago, ritastrakosha said:

Studies published in scientific journals are not "anything".

I doubt you are accurately representing what they say. (Purely based on what you have posted on this forum)

15 minutes ago, ritastrakosha said:

 Can you bring references for "There is more aluminium in a cup of tea." statement?

"The mean values of total concentrations of aluminium found were (0.91 ± 0.31) g/kg for green tea, (0.76 ± 0.38) g/kg for black tea, (0.23 ± 0.09) g/kg for herbal tea and (0.22 ± 0.08) g/kg for fruit tea. For the tea infusions (4.33 ± 0.35) mg/L for green tea, 4.40 mg/L for black tea, 0.52 mg/L for herbal tea and (0.12 ± 0.02) mg/L for fruit tea. These results are in good agreement with literature data."

http://research.fh-ooe.at/files/publications/3145_KROEPPL.pdf

So just over 1mg per cup (250ml) of tea.

The amount of aluminium in a dose of vaccine is generally less than half a mg: https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-ingredients/aluminum

And there is no evidence that aluminium has any harmful effects. 

[StringJunky]

28 minutes ago, Strange said:

I doubt you are accurately representing what they say. (Purely based on what you have posted on this forum)

"The mean values of total concentrations of aluminium found were (0.91 ± 0.31) g/kg for green tea, (0.76 ± 0.38) g/kg for black tea, (0.23 ± 0.09) g/kg for herbal tea and (0.22 ± 0.08) g/kg for fruit tea. For the tea infusions (4.33 ± 0.35) mg/L for green tea, 4.40 mg/L for black tea, 0.52 mg/L for herbal tea and (0.12 ± 0.02) mg/L for fruit tea. These results are in good agreement with literature data."

http://research.fh-ooe.at/files/publications/3145_KROEPPL.pdf

So just over 1mg per cup (250ml) of tea.

The amount of aluminium in a dose of vaccine is generally less than half a mg: https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-ingredients/aluminum

And there is no evidence that aluminium has any harmful effects. 

I hope she didn't breast feed her children, with there being 14x more than in a vaccine.

I feel like joining a few antivaccer forums and upsetting their deluded apple cart. It makes me mad.

Edited November 15, 2018 by StringJunky

[ritastrakosha]

Aluminium is added to the vaccine to increase the immune response to the virus/microbe. If its effect on immunity would be the same with the ingested aluminium, why bother add it to the vaccine? Infants already have hundreds of foreign chemicals in their bodies when they are born. Vaccines further add to the burden with aluminium, virus and microbe particles.  

Aluminum vaccine adjuvants: are they safe?

Tomljenovic L1, Shaw CA.
Author information
Abstract
Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants, medical science's understanding about their mechanisms of action is still remarkably poor. There is also a concerning scarcity of data on toxicology and pharmacokinetics of these compounds. In spite of this, the notion that aluminum in vaccines is safe appears to be widely accepted. Experimental research, however, clearly shows that aluminum adjuvants have a potential to induce serious immunological disorders in humans. In particular, aluminum in adjuvant form carries a risk for autoimmunity, long-term brain inflammation and associated neurological complications and may thus have profound and widespread adverse health consequences. In our opinion, the possibility that vaccine benefits may have been overrated and the risk of potential adverse effects underestimated, has not been rigorously evaluated in the medical and scientific community. We hope that the present paper will provide a framework for a much needed and long overdue assessment of this highly contentious medical issue.

Slow CCL2-dependent translocation of biopersistent particles from muscle to brain

•    Zakir Khan,
•    Christophe Combadière,
•    François-Jérôme Authier,
•    Valérie Itier,
•    François Lux,
•    Christopher Exley,
•    Meriem Mahrouf-Yorgov,
•    Xavier Decrouy,
•    Philippe Moretto,
•    Olivier Tillement,
•    Romain K Gherardi†Email author and
•    Josette Cadusseau†Email author
BMC Medicine201311:99
https://doi.org/10.1186/1741-7015-11-99
Abstract
Background
Long-term biodistribution of nanomaterials used in medicine is largely unknown. This is the case for alum, the most widely used vaccine adjuvant, which is a nanocrystalline compound spontaneously forming micron/submicron-sized agglomerates. Although generally well tolerated, alum is occasionally detected within monocyte-lineage cells long after immunization in presumably susceptible individuals with systemic/neurologic manifestations or autoimmune (inflammatory) syndrome induced by adjuvants (ASIA).
Results
Intramuscular injection of alum-containing vaccine was associated with the appearance of aluminum deposits in distant organs, such as spleen and brain where they were still detected one year after injection. Both fluorescent materials injected into muscle translocated to draining lymph nodes (DLNs) and thereafter were detected associated with phagocytes in blood and spleen. Particles linearly accumulated in the brain up to the six-month endpoint; they were first found in perivascular CD11b+ cells and then in microglia and other neural cells. DLN ablation dramatically reduced the biodistribution. Cerebral translocation was not observed after direct intravenous injection, but significantly increased in mice with chronically altered blood-brain-barrier. Loss/gain-of-function experiments consistently implicated CCL2 in systemic diffusion of Al-Rho particles captured by monocyte-lineage cells and in their subsequent neurodelivery. Stereotactic particle injection pointed out brain retention as a factor of progressive particle accumulation.
Conclusion
Nanomaterials can be transported by monocyte-lineage cells to DLNs, blood and spleen, and, similarly to HIV, may use CCL2-dependent mechanisms to penetrate the brain. This occurs at a very low rate in normal conditions explaining good overall tolerance of alum despite its strong neurotoxic potential. However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of overimmunization or immature/altered blood brain barrier or high constitutive CCL-2 production.
 

 

Edited November 16, 2018 by ritastrakosha
typo

[StringJunky]

57 minutes ago, ritastrakosha said:

Aluminium is added to the vaccine to increase the immune response to the virus/microbe. If its effect on immunity would be the same with the ingested aluminium, why bother add it to the vaccine? Infants already have hundreds of foreign chemicals in their bodies when they are born. Vaccines further add to the burden with aluminium, virus and microbe particles.  

Aluminum vaccine adjuvants: are they safe?

Tomljenovic L1, Shaw CA.
Author information
Abstract
Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants, medical science's understanding about their mechanisms of action is still remarkably poor. There is also a concerning scarcity of data on toxicology and pharmacokinetics of these compounds. In spite of this, the notion that aluminum in vaccines is safe appears to be widely accepted. Experimental research, however, clearly shows that aluminum adjuvants have a potential to induce serious immunological disorders in humans. In particular, aluminum in adjuvant form carries a risk for autoimmunity, long-term brain inflammation and associated neurological complications and may thus have profound and widespread adverse health consequences. In our opinion, the possibility that vaccine benefits may have been overrated and the risk of potential adverse effects underestimated, has not been rigorously evaluated in the medical and scientific community. We hope that the present paper will provide a framework for a much needed and long overdue assessment of this highly contentious medical issue.

Slow CCL2-dependent translocation of biopersistent particles from muscle to brain

•    Zakir Khan,
•    Christophe Combadière,
•    François-Jérôme Authier,
•    Valérie Itier,
•    François Lux,
•    Christopher Exley,
•    Meriem Mahrouf-Yorgov,
•    Xavier Decrouy,
•    Philippe Moretto,
•    Olivier Tillement,
•    Romain K Gherardi†Email author and
•    Josette Cadusseau†Email author
BMC Medicine201311:99
https://doi.org/10.1186/1741-7015-11-99
Abstract
Background
Long-term biodistribution of nanomaterials used in medicine is largely unknown. This is the case for alum, the most widely used vaccine adjuvant, which is a nanocrystalline compound spontaneously forming micron/submicron-sized agglomerates. Although generally well tolerated, alum is occasionally detected within monocyte-lineage cells long after immunization in presumably susceptible individuals with systemic/neurologic manifestations or autoimmune (inflammatory) syndrome induced by adjuvants (ASIA).
Results
Intramuscular injection of alum-containing vaccine was associated with the appearance of aluminum deposits in distant organs, such as spleen and brain where they were still detected one year after injection. Both fluorescent materials injected into muscle translocated to draining lymph nodes (DLNs) and thereafter were detected associated with phagocytes in blood and spleen. Particles linearly accumulated in the brain up to the six-month endpoint; they were first found in perivascular CD11b+ cells and then in microglia and other neural cells. DLN ablation dramatically reduced the biodistribution. Cerebral translocation was not observed after direct intravenous injection, but significantly increased in mice with chronically altered blood-brain-barrier. Loss/gain-of-function experiments consistently implicated CCL2 in systemic diffusion of Al-Rho particles captured by monocyte-lineage cells and in their subsequent neurodelivery. Stereotactic particle injection pointed out brain retention as a factor of progressive particle accumulation.
Conclusion
Nanomaterials can be transported by monocyte-lineage cells to DLNs, blood and spleen, and, similarly to HIV, may use CCL2-dependent mechanisms to penetrate the brain. This occurs at a very low rate in normal conditions explaining good overall tolerance of alum despite its strong neurotoxic potential. However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of overimmunization or immature/altered blood brain barrier or high constitutive CCL-2 production.
 

 

The authors of that paper are known antivaccers in the Andrew Wakefield mould.

Quote

Retracted HPV vaccine article – Shaw and Tomljenovic are back

Earlier this year, I wrote a post about a retracted HPV vaccine article, “Behavioral abnormalities in young female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil,” published in the one of the top journals in the field, Vaccine. This article was authored by, among others, the leading lights of the academic side of the anti-vaccine movement – Christopher Shaw,  Lucija Tomljenovic and Yehuda Schoenfeld. In particular, Shaw and Tomljenovic seem to have an obsession with the HPV vaccine.

After withering criticism across the field, especially since the article was published in a prestigious, high impact factor journal, the editors at Vaccine decided to withdraw the article:

This article has been withdrawn at the request of the Editor-in-Chief due to serious concerns regarding the scientific soundness of the article. Review by the Editor-in-Chief and evaluation by outside experts, confirmed that the methodology is seriously flawed, and the claims that the article makes are unjustified. "As an international peer-reviewed journal we believe it is our duty to withdraw the article from further circulation, and to notify the community of this issue".

https://www.skepticalraptor.com/skepticalraptorblog.php/retracted-hpv-vaccine-article-shaw-tomljenovic/

 

Edited November 16, 2018 by StringJunky

[koti]

On 28.02.2018 at 10:11 PM, koti said:

Alleged correlation of acetaminophen with ASD is almost as equally absurd as alleged correlation of homosexuality with light bulbs and sleep deprivation:
https://pacifictribune.com/2017/05/29/rita-strakosha-links-gayness-light/

 

 

@StringJunky "Naps a a cure" ^^

I don't know if you missed my above post from 9 months ago, jus making sure.

[coffeesippin]

On 11/15/2018 at 7:59 AM, ritastrakosha said:

Viruses are triggers for inflammatory diseases. Bacteria are triggers for inflammatory diseases. Heavy metals, like aluminum, are triggers for inflammatory diseases. But vaccines, which have all of these, cannot cause any problems?! Yehuda Shoenfeld is much more up to date with vaccines and immunity than Wakefield (but Wakefield was a pioneer). I recommend you read Shoenfeld. There are diseases which are not transmittable (tetanus), there are vaccines which do not impede transmission (pertussis vaccine), there are vaccinated people who spread the disease they are vaccinated against (influenza), there are diseases which are less dangerous than the diseases that vaccines exacerbate (mumps versus asthma), there are facultative vaccines, and there are children genetically susceptible to autoimmune diseases. In all these cases, it is better left to the individual to vaccinate or not. 

Fully agreed.

[Strange]

3 minutes ago, coffeesippin said:

Fully agreed.

What a surprise 

[coffeesippin]

On 11/15/2018 at 11:56 AM, CharonY said:

Also note that after Wakefield many folks looked into the link and if one does not cherry pick or falsify data, the association vanishes. Meanwhile, lack of immunization has brought back diseases that were on the brink of vanishing, and children pay the price for that. 

Lack of sexual propriety has brought back diseases which were on the brink of extinction 10 years ago, and children can pay the price for that too, not that I'm saying studies done showing links with autism and autism wrong, but no one seems to be saying 'keep it in your pants' in the same way a lot of people say 'if you don't get vaccinated you're a criminal.'   https://www.cdc.gov/media/releases/2017/p0926-std-prevention.html

4 minutes ago, Strange said:

What a surprise 

It shouldn't be, Strange, I believe in freedom and individual liberty.  I believe in the right of conscience based on many things including the accumulation of information.  I believe in, for instance, massively promoting the cleaning of air cooling and heating systems ahead of mass immunizations for people who don't need them IF they clean their systems.    

Edited November 18, 2018 by coffeesippin
forgot to include link

[Strange]

4 minutes ago, coffeesippin said:

Lack of sexual propriety has brought back diseases which were on the brink of extinction 10 years ago, and children can pay the price for that too, not that I'm saying studies done showing links with autism and autism wrong, but no one seems to be saying 'keep it in your pants' in the same way a lot of people say 'if you don't get vaccinated you're a criminal.'   https://www.cdc.gov/media/releases/2017/p0926-std-prevention.html

!

Moderator Note

Stick to the topic please 

 

[koti]

On 15.11.2018 at 1:59 PM, ritastrakosha said:

Viruses are triggers for inflammatory diseases. Bacteria are triggers for inflammatory diseases. Heavy metals, like aluminum, are triggers for inflammatory diseases. But vaccines, which have all of these, cannot cause any problems?! Yehuda Shoenfeld is much more up to date with vaccines and immunity than Wakefield (but Wakefield was a pioneer). I recommend you read Shoenfeld. There are diseases which are not transmittable (tetanus), there are vaccines which do not impede transmission (pertussis vaccine), there are vaccinated people who spread the disease they are vaccinated against (influenza), there are diseases which are less dangerous than the diseases that vaccines exacerbate (mumps versus asthma), there are facultative vaccines, and there are children genetically susceptible to autoimmune diseases. In all these cases, it is better left to the individual to vaccinate or not. 

Didn't you mean to say that Wakefield wasn't a pioneer but instead is a fraud who has been convicted in court and stripped of his medical license - over a decade ago?
Oh wait, I'm not surprised - you claim that "homosexuality is directly tied to fats, sugars, and alcohol. She also claims cutting these things out from your diet could “decrease and… prevent the return of homosexual attractions" so I wouldn't expect anything less from you than antivaccine conspiracy theories. Is there an end to your bad science or are you just getting warmed up? If you're just getting warm up I would expect you to reach "pioneer level" of Andrew Wakefield pretty soon.

https://www.bmj.com/content/342/bmj.c5258

https://www.queerty.com/study-claims-fast-food-consumption-sleep-depravation-cause-homosexuality-20170530

[coffeesippin]

14 minutes ago, coffeesippin said:

Fully agreed.

An article I looked through says one of the possible causes for acetaminophen to possibly lead to autism is that it lowers the temperature of an ill child, higher temperatures are needed to kill invading agents.    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044872/

On 11/15/2018 at 5:25 PM, StringJunky said:

 

Many vaccines with it in have up to a 0.5mg aluminium adjuvant.  Breast fed infants ingest about 7mg; 14  times what's in vaccines. If you want the list of Aluminium amounts in each vaccine click the link above.

Eating and digesting aluminum is far different than having it injected into the bloodstream.  

[koti]

41 minutes ago, coffeesippin said:

Eating and digesting aluminum is far different than having it injected into the bloodstream.  

How different would it be exactly? If you injected vaccines into the bloodstream that is, which you ofcourse don't.

60mg max and 45mg med are the daily dosages of aluminium for a human (it's the third most common element in earths crust)  Max dosage of aluminum adjuvant in a vaccine is 1,25mg, delivered intramuscular. You ingest more aluminium from drinking a coke can or from antiperspirants or from breast milk than from vaccines. Living in a city, you literally breath orders of magnitude more of aluminum in a month than present in all vaccines you could ever inject in your life. 

 

http://www.harpocratesspeaks.com/2015/02/demystifying-vaccine-ingredients-aluminum.html?fbclid=IwAR1bz5vjWW98S5qFpAWkW1xIxuwzry4dqoUW4sHZjOZO0hTgZG8x_FEU1cg

 

https://mainstreamparenting.wordpress.com/2008/09/07/so-whats-the-deal-with-aluminum-in-vaccines-anyway-part-ii/?fbclid=IwAR3iEEiWAZibIfuywWPv1IHJzncIvOLIiPQ1iU-z9H6rzLwZg5rLrTpsJPQ

 

Edited November 18, 2018 by koti

[coffeesippin]

2 minutes ago, koti said:

How different would it be exactly? If you injected vaccines into the bloodstream that is, which you ofcourse don't.
 

I suppose it would be as different as injecting an aspirin or swallowing it, but if you're a medical professional let me know how different you think it would be.    Thanks for your information about vaccination which I googled to confirm.  I've had no experience with vaccine since Elementary school 55 or more years ago so I haven't thought about it except in the past several years when it reached the news about autism, and I saw right away the science was poor on either side, but what I know about the vaccination discussion is the side of the argument which says YOU MUST BELIEVE IN VACCINES are in general very loud and insulting towards those who don't want the vaccine,  while the side that says,  'No after careful consideration I've decided not to get the vaccination'  is quiet and unassuming.  I've seen that in flesh and blood life and in internet discussions.   

[koti]

6 minutes ago, coffeesippin said:

... I know about the vaccination discussion is the side of the argument which says YOU MUST BELIEVE IN VACCINES are in general very loud and insulting towards those who don't want the vaccine,  while the side that says,  'No after careful consideration I've decided not to get the vaccination'  is quiet and unassuming.  I've seen that in flesh and blood life and in internet discussions.   

If I tell you politely, quietly and unassumingly to eat your own excrements becasue it's actually very healthy and most of all 100% natural - would you consider? 

By the way...about 60% of aluminium present in a vaccine are expelled from the infants body in the first 24 hours after the injection, about 3/4 is expelled after a week. The rest stays in bones, tissue, brain and is delt with by the body in next years of life. You still get more "damage" from eating a sandwich wrapped in aluminum foil. 

 

Edited November 18, 2018 by koti

[coffeesippin]

1 minute ago, koti said:

If I tell you politely, quietly and unassumingly to eat your own excrements becasue it's actually very healthy and most of all 100% natural - would you consider? 
 

I would consider you a vulgar and unthinking person incapable of discussing any topic intelligently unless you had a radical transformation of your morality and intellect, so that while you may have valuable information I couldn't trust anything you said.

[koti]

Just now, coffeesippin said:

I would consider you a vulgar and unthinking person incapable of discussing any topic intelligently unless you had a radical transformation of your morality and intellect, so that while you may have valuable information I couldn't trust anything you said.

But why? It's 100% natural.

[coffeesippin]

1 minute ago, koti said:

But why? It's 100% natural.

But you're not .. you've been transformed into a image of a 'real man' who needs to be vulgar to be a 'real man.'  That transformation happened slowly of course, and as a natural boy you resisted it because you knew it to be fake and obscene.  Nevertheless, once you grew to enjoy the feeling of power it gave you over others you allowed it to grow, diminishing the natural man who cares about others, who needs acceptance by others, and pushing yourself ever deeper into a pit from which you can't seem to escape.

[StringJunky]

8 minutes ago, coffeesippin said:

I suppose it would be as different as injecting an aspirin or swallowing it, but if you're a medical professional let me know how different you think it would be.    Thanks for your information about vaccination which I googled to confirm.  I've had no experience with vaccine since Elementary school 55 or more years ago so I haven't thought about it except in the past several years when it reached the news about autism, and I saw right away the science was poor on either side, but what I know about the vaccination discussion is the side of the argument which says YOU MUST BELIEVE IN VACCINES are in general very loud and insulting towards those who don't want the vaccine,  while the side that says,  'No after careful consideration I've decided not to get the vaccination'  is quiet and unassuming.  I've seen that in flesh and blood life and in internet discussions.   

The problem is that the collective societal memory of the scourge that these diseases were is slowly being forgotten. Not many people have direct memories of the problems and extent of these diseases. To many  .people below a certain age, the purpose of vaccines is just an abstract concept for which one can choose to have or not with minimal consequences. The vaccination programs have become victims of their own success. I am reminded of the saying "Lest we forget"... history will repeat  itself.