akromyk Posted March 27, 2018 Share Posted March 27, 2018 Let's say we have a male with infertility issues. Him and his wife get a Chromosomal Analysis that comes back with his wife being fine, but him having: "balanced reciprocal translocation between chromosomes one and ten" 46,XY,t(1;10)(q21;q25.2) And the embryos from their first IVF round have the following abnormalities: 45,XY,dup(1)(q23q44),del(10)(q26),-22 46,XY,del(1)(q23),dup(10)(q26q26) Why would the embryos have duplications and deletions on the same chromosome but at different locations than the abnormalities in the potential father? Link to comment Share on other sites More sharing options...
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