Genetic Manipulation Within the body - HLA-B27

[jkk]

Hello

Is it possible that this type HLA-B27 can be altered, snipped, cut, edited, replaced, switched off  in the human body ?

https://en.wikipedia.org/wiki/HLA-B27

This is a common gene highly implicated in many diseases of the immune system...one way or another taking it out of the equation I would hope be life changing for the positive if a way could be found.

Trying to find out for my own research ..as someone who suffers from the gene...as do many.

If it is possible or not please could the reply take the time time to explain as much as possible the reasons for or against the possibilities.

Thankyou.