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Posted

Hello, I'd like to determine the standard free energy for aerobic glycolysis (from glucose to pyruvate). My question is: in order to do it, can I sum the standard free energy values of the 10 reactions involved in the pathway, multiplying by two the standard free energies for the reactions of the harvesting phase? Is it a good method? Am I doing something wrong? 

Thanks in advance. 

Posted

Biochemistry often use a different standard state than other branches of chemistry, one in which the concentration of protons is taken to be 1 x 10-7 M.  The standard free energy of glycolysis can be found in many biochemistry textbooks.  However, as a learning exercise, I don't see anything wrong with your working it out for yourself.

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