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Posted (edited)

It's a very promising technology but it has to develop/evolve a lot. Many teams attempt to correct disease-causing mutations in human embryos .

I'm very curious to how this technology will develop since you can edit the DNA of animals and plants.

Edited by Itoero
Posted (edited)

Essentially all the chromosomes need to exist inside the nucleus, not outside. It's like football and you need to get it into the nucleus to touch down. So transformer wise, we smuggle DNA sequence in chunks(like messenger RNA)  through the nucleus pore into the nucleus, and we assemble an entire chromosome inside the nucleus with DNA ligase. What I want to do with Crispr Cas9 is to destroy the original chromosome else having 3 copies of a chromosome could be a problem.

 

P.S. Like 2 million pieces of DNA, assemble by hand/automatic

Edited by fredreload

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