Aconitin Posted May 8, 2020 Posted May 8, 2020 Hello! I have a question regarding H1-antihistamines. It is said, that first generation antihistamines are used to treat nausea because they can cross the blood-brain-barrier and reach the vomiting centre. However, I read that the vomiting centre is not protected by the blood-brain-barrier. So is the ability to cross the blood-brain-barrier irrelevant for H1-antihistamines? Greetings, Aconitin
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