Anchovyforestbane Posted November 16, 2020 Share Posted November 16, 2020 Where does the amino acid at the acceptor stem of tRNA come from? Where are the amino acids synthesized, if not from the tRNA itself, and how does it make its way to the acceptor stem in the first place; what role specifically does the anticodon pairing play in this? And if it is synthesized from the tRNA, how does the tRNA remain unaltered afterwards, and how specifically does the anticodon pairing effect this? Link to comment Share on other sites More sharing options...
BabcockHall Posted November 18, 2020 Share Posted November 18, 2020 Amino acids are synthesized from their own pathways, entirely separate from the synthesis of RNA. A family of twenty aminoacyl tRNA synthetase enzymes is responsible for joining the amino acid to its cognate tRNA. These are questions and topics that it takes a biochemistry textbook chapters to develop. 1 Link to comment Share on other sites More sharing options...
Anchovyforestbane Posted November 18, 2020 Author Share Posted November 18, 2020 40 minutes ago, BabcockHall said: Amino acids are synthesized from their own pathways, entirely separate from the synthesis of RNA. A family of twenty aminoacyl tRNA synthetase enzymes is responsible for joining the amino acid to its cognate tRNA. These are questions and topics that it takes a biochemistry textbook chapters to develop. I see, thank you for explaining. Do you know of any sources which describe this process in optimal detail? Link to comment Share on other sites More sharing options...
BabcockHall Posted November 18, 2020 Share Posted November 18, 2020 Nelson and Cox's Principles of Biochemistry. 1 Link to comment Share on other sites More sharing options...
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