Vreesie Posted December 10, 2020 Share Posted December 10, 2020 In blood genotyping the letter I/i is used (IA, IB, i) to define the alleles. Why is the letter I/i used or where does it stand for? I couldn’t find anything on the internet... Link to comment Share on other sites More sharing options...
StringJunky Posted December 10, 2020 Share Posted December 10, 2020 (edited) I think it means whether an allele is dominant or recessive; 'I' is the dominant form and 'i' recessive. There's a table on genotypes in each of these links that might make clearer: https://www2.nau.edu/lrm22/lessons/blood_type/blood_type.html http://blog.cambridgecoaching.com/an-introduction-to-blood-types-genotype-phenotype-inheritance-transfusion-and-more Edited December 10, 2020 by StringJunky Link to comment Share on other sites More sharing options...
Dord Posted December 10, 2020 Share Posted December 10, 2020 4 hours ago, Vreesie said: Why is the letter I/i used or where does it stand for? Isoagglutinogen https://medical-dictionary.thefreedictionary.com/isoagglutinogen#:~:text=(ī′sō-ăg′,to which it is attached. Link to comment Share on other sites More sharing options...
Dord Posted December 12, 2020 Share Posted December 12, 2020 Apologies, I omitted the following in error... Quote The ABO blood type is controlled by a single gene (the ABO gene) with three types of alleles inferred from classical genetics: i, IA, and IB. The I designation stands for isoagglutinogen, another term for antigen. https://en.m.wikipedia.org/wiki/ABO_blood_group_system#:~:text=The I designation stands for,the red blood cell antigens. Sourced from: Klug, William S.; Cummings, Michael R. (1997). Concepts of Genetics (5th ed.). Link to comment Share on other sites More sharing options...
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