Theoretical Idea on Genetics: SRY Gene and XX chromosomes

[The Researcher]

As I write this I researched on coronavirus. The MRNA is genetic material that makes the coronavirus multiply inside the infected one.

 

Now I wonder if this MRNA can be used to shut off SRY gene and to start multiplying XX chromosomes?

 

What do you think about my Theoretical Idea?

[Endy0816]

I know SRY deals mainly with Testes development, so not sure what disabling it might cause in a developed individual.

Strictly speaking only need the one X though this can itself cause issues.

[The Researcher]

1 hour ago, Endy0816 said:

Strictly speaking only need the one X though this can itself cause issues.

Mmm what kind of issues would arise?

[Endy0816]

4 hours ago, The Researcher said:

Mmm what kind of issues would arise?

Be in the range of either Swyer or Turner Syndrome.

 

Quote

XY gonadal dysgenesis, also known as Swyer syndrome, is a type of hypogonadism in a person whose karyotype is 46,XY. Though they typically have normal female external genitalia,[1] the person has functionless gonads, fibrous tissue termed "streak gonads", and if left untreated, will not experience puberty. Such gonads are typically surgically removed (as they have a significant risk of developing cancer). The typical medical treatment is hormone replacement therapy.[2];

https://en.wikipedia.org/wiki/XY_gonadal_dysgenesis

 

Quote

Turner syndrome (TS), also known as 45,X, or 45,X0, is a genetic condition in which a female is partly or completely missing an X chromosome.[2]

Signs and symptoms vary among those affected.[1] Often, a short and webbed neck, low-set ears, low hairline at the back of the neck, short stature, and swollen hands and feet are seen at birth.[1] Typically, they develop menstrual periods and breasts only with hormone treatment, and are unable to have children without reproductive technology.[1] Heart defects, diabetes, and low thyroid hormone occur more frequently.[1] Most people with TS have normal intelligence; however, many have troubles with spatial visualization that may be needed for mathematics.[1] Vision and hearing problems occur more often.[5]

https://en.wikipedia.org/wiki/Turner_syndrome

 

In theory, if we understood things better we could reprogram without causing issues though. 

[The Researcher]

Inactive SRY gene kills testes creation

But no 2nd X chromosome prevents ovaries from creating

 

This was my takeaway from a YouTube video

 

Now my question is how can I create the 2nd X in XX chromosome?

[The Researcher]

I have a belief that changing DNA can alter organ production. For example if I replace the Y in XY with a X to equal XX; the long term result will be the former XY person growing female organs. Did I get it on point?

 

Looking forward to your replies.