astatine Posted September 23, 2005 Posted September 23, 2005 can i form a mannich base out of phenylacetaldehyde , phenol and a seconday amine? if yes would the reaction take place at the ortho or para position of the phenol. and would the prodckt be a 1,2-diarylamine derivative? i have read that phenols form a mannich whit aldehydes and sec.amines. but i,,m not sure if a aromatic aldehyde like phenylacetaldehyde works too as a aldehyde. thank you kindly
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