johndohnal Posted March 6 Posted March 6 Hi All, I'm looking for a PDB for 7α-hydroxylase CYP7A1 in complex with cholesterol. I've searched in the PDB database and I've found the files for the enzyme alone, and complexed with cholest-4-en-3-one and 7-ketocholesterol, but not complexed with cholesterol. This seems odd to me as cholesterol is its natural substrate. Is it possible that the PDB file doesn't exist, or am I missing something? Thanks! John
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