nec209 Posted August 14 Posted August 14 Scientists find humans age dramatically in two bursts – at 44, then 60 US findings suggesting ageing is not a slow and steady process could explain spikes in health issues at certain ages If you have noticed a sudden accumulation of wrinkles, aches and pains or a general sensation of having grown older almost overnight, there may be a scientific explanation. Research suggests that rather than being a slow and steady process, aging occurs in at least two accelerated bursts. The study, which tracked thousands of different molecules in people aged 25 to 75, detected two major waves of age-related changes at around ages 44 and again at 60. The findings could explain why spikes in certain health issues including musculoskeletal problems and cardiovascular disease occur at certain ages. https://www.theguardian.com/science/article/2024/aug/14/scientists-find-humans-age-dramatically-in-two-bursts-at-44-then-60-aging-not-slow-and-steady
CharonY Posted August 14 Posted August 14 There are also studies corroborating this, such as changes in energy metabolism, which happens in stages. There are likely tipping points of processes that contribute to that (and which we do not fully understand yet).
iNow Posted August 14 Posted August 14 I’m curious how they controlled for environmental factors like stress from kids, stress from work, changing lifestyles and moving away from sports, heavier alcohol use and sedentary, etc
CharonY Posted August 14 Posted August 14 44 minutes ago, iNow said: I’m curious how they controlled for environmental factors like stress from kids, stress from work, changing lifestyles and moving away from sports, heavier alcohol use and sedentary, etc They didn't. It is a multi-omics study with samples taken over a period of a few years from healthy individuals. So the longitudinal data per person is fairly short (but for these types of studies still a bit more extensive, as most only have single time point per person). Adjustments were, I believe mostly with regard to factors such as BMI, insulin resistance and so on. However, due to the cohort, the data in necessarily aggregated for a view over time.
nec209 Posted August 14 Author Posted August 14 1 hour ago, iNow said: I’m curious how they controlled for environmental factors like stress from kids, stress from work, changing lifestyles and moving away from sports, heavier alcohol use and sedentary, etc I don’t think the study look at those factors.
Recommended Posts