Pain receptors regulate body temperature ??!?!?!?

[chuinhen]

A

 

 

http://edition.cnn.com/2006/HEALTH/conditions/01/27/rare.conditions/index.html

 

 

"Other abnormalities quickly surfaced. Roberto was severely susceptible to heatstroke on hot summer days. His parents soon noticed he did not sweat."

 

 

 

B

 

http://edition.cnn.com/2006/HEALTH/conditions/02/03/btsc.oppenheim/index.html

 

 

"her brain doesn't receive signals that she's experiencing pain, and she hardly sweats."

 

 

 

 

 

I Tought hotness is detected by thermoreceptors under the skin !!!!

From the 2 casses above ,it seems like pain receptors plays a role in thermoreceptor !!!

 

Quite strange ?!?!?!

[scicop]

not at all strange. The detection of pain in the perifery (such as by thermoreceptors) is transmitted through the neurocircuitry, that involves a number of connections. Whereas thermoreceptors/mechno receptors may detect pain there are a number of neurotransmitters as well as a number of receptors systems that partake in transmitting pain to the CNS. These systems include substance P (your neurokinins), vanilloid compounds, some opioid peptides, as well as some adrenergic activity. In addition there is the circuitry, involving A and C fibres in the dorsal horn of the spinal cord. Any defect (i.e. genetic) in anyone of the receptors systems/circuitry can lead to inhibition of pain transmission seen with those examples you provided.

[Glider]

Polymodal fibres (C fibres) are assocated with the detection of temperature change and noxious heat (>40 C). These are also 'slow' pain fibres (A delta are 'fast' pain fibres). So C fibres are doing both really; detecting changes in temperature and, above a certain threshold, acting as nociceptors.