Syntesis

[Bibinou]

Hello,

 

how can we make these reactions?

 

 

thank you

[ecoli]

NaNH2 an aldehyde and H+, perhaps? Though, you'd have to hydrogenate the triple bond, and I'm not sure if you're allowed to use that many steps.

[John Cuthber]

ecoli, What aldehyde and what triple bond?

 

The classic method for the first part, IIRC, is reduction by magnesium. Look for stuff about pinacol.

I'm not sure abouty the second; perhaps dehydration to the epoxide then reduction?

[ecoli]

ecoli, What aldehyde and what triple bond?

 

carbon forming bonds in a reaction with a ketone and a triple bond. The ketone turns into an alcohol if you add H+.

 

Though, the pinacol would make more sense.

 

edit: never mind, I can't count carbon - carbon bonds. That wouldn't work.

[Bluenoise]

I think the first one is something simular to an aldol condensation. Actually I'm nearly 100% positive it's related in some manner. I just can tell you cuz I left all my notes in another city and the internet sucks for this...

Maybe in a couple weeks when I pick them up sorry....

[John Cuthber]

"I think the first one is something simular to an aldol condensation. Actually I'm nearly 100% positive it's related in some manner."

I'm pretty certain that it's not (other than that it forma a carbon carbon bond). I also wonder if you actually looked into the chemistry of pinacol. Even a google search on the word might have helped, and I think the 'net's really quite good at that sort of thing.