ydoaPs Posted February 19, 2007 Posted February 19, 2007 I'm confused. The bottle says "safe as coffee" and "The recommended dose of this product contains about as much caffeine as a cup of coffee" yet it also says "take 1/2 to 1 caplet not more often than every 3 to 4 hours." I've coffee at a rate far greater than one cup every three to four hours before with no ill effects, so I'm confused. Is the bottle exaggerating, or do I have a tolerance from years of caffeine use? Each pill is 200mg. Either way, they keep me awake during class.
insane_alien Posted February 19, 2007 Posted February 19, 2007 the amount of caffeine is probably less than 200 mg per pill. LD 50/50 is around 2500 mg anyway. 2 an hour would probably be perfectly fine but depending on your tolerances any more might have unwanted effects.
Phi for All Posted February 19, 2007 Posted February 19, 2007 Most likely the dosage recommendation errs on the side of caution. For some people a cup of coffee too late in the day would ensure sleeplessness that night so the NoDoz could have the same effect. People like you that have a higher tolerance for caffeine may have to adjust your intake accordingly, but I don't think it's a good idea to slam three of them with a scone like you might with java. Once it's already in your system it's harder to correct too large a dose.
YT2095 Posted February 19, 2007 Posted February 19, 2007 the amount of caffeine is probably less than 200 mg per pill. LD 50/50 is around 2500 mg anyway. say What! per what unit mass???? LD 50 is measured in Dose per Kg, I can assure you that 2.5g per kilo is Far above the MORE THAN lethal dose for cafeine!
ydoaPs Posted February 19, 2007 Author Posted February 19, 2007 say What! per what unit mass???? LD 50 is measured in Dose per Kg, I can assure you that 2.5g per kilo is Far above the MORE THAN lethal dose for cafeine! Out of curiosity, what IS the lethal dose of caffeine?
YT2095 Posted February 19, 2007 Posted February 19, 2007 I wouldn`t have said anymore than 200mg per Kg at the absolute Max! is mem serves correctly. I could be wrong, but I think it`s roughly Something like that (or in that ball park).
insane_alien Posted February 19, 2007 Posted February 19, 2007 say What! per what unit mass???? LD 50 is measured in Dose per Kg, I can assure you that 2.5g per kilo is Far above the MORE THAN lethal dose for cafeine! oh sorry, thats just for an average 80 kg human
ydoaPs Posted February 19, 2007 Author Posted February 19, 2007 200mg per Kg of what? 200mg per Kg of body mass?
Callipygous Posted February 19, 2007 Posted February 19, 2007 well yeah, what else would it be? most people dont think that much in depth. when i think lethal dosage i think of it in terms of the average person, not per kilo, or whatever the actual standard is. granted, im pretty sure im wrong for doing so.
Mokele Posted February 20, 2007 Posted February 20, 2007 LD50 of oral caffeine in rats: 192 mg/kg Translated to human terms, that means I'd have to ingest a bit less than 19 grams to have a 50/50 chance of dying.
raptor Posted October 4, 2007 Posted October 4, 2007 I'm confused. The bottle says "safe as coffee" and "The recommended dose of this product contains about as much caffeine as a cup of coffee" yet it also says "take 1/2 to 1 caplet not more often than every 3 to 4 hours." I've coffee at a rate far greater than one cup every three to four hours before with no ill effects, so I'm confused. Is the bottle exaggerating, or do I have a tolerance from years of caffeine use? Each pill is 200mg. Either way, they keep me awake during class. They're just recommending safe levels, and you probably shouldn't have that much caffeine over long periods as it can lead to health problems such as heart arrythmias even if the acute symptoms aren't that bad.
DrDNA Posted October 4, 2007 Posted October 4, 2007 I think one difference in the way Nodoz acts phyisologically is the way you take it compared to coffee. What does it take, 20-30 mins on average to drink 2 cups of coffee? But if you take a couple of pills, the caffine should hit your bloodstream much faster. Not fast enough for a bolus effect like you would get from smoking, injecting or snorting a substance, but probably much more of a quick jolt than you get from sipping a dilute, hot drink.
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