science07 Posted April 24, 2007 Posted April 24, 2007 Is it t-dependent or t-independent and why? I say t-dependent and cited the definition. Not sure that is right, though. TIA
blike Posted April 24, 2007 Posted April 24, 2007 Are you talking about t-cell mediated hypersensitivity reactions? T-cell mediated hypersensitivity reactions ("type IV hypersensitivity reactions") are also called "delayed type" hypersensitivity reactions because, as their name implies, they take a few days to fully develop. This is because they are cell mediated rather than antibody or immune complex mediated. I would suggest that you look into type-I hypersensitivity reactions. These are mediated by IgE secreted from plasma cells, which then binds to mast cells (and basophils) releasing histamine and leukotriene. Look these up and see if they are t-cell dependent. Good luck!
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